1-methylamino-2-methylcyclopentane | 683222-31-3

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 1-methylamino-2-methylcyclopentane
• 英文别名: N,2-Dimethylcyclopentan-1-amine
• CAS: 683222-31-3
• 化学式: C₇H₁₅N
• 分子量: 113.203
• InChiKey: MEDVLGKKCCKQAO-UHFFFAOYSA-N

物化性质

• 沸点：
  129.2±8.0 °C(Predicted)
• 密度：
  0.84±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  8
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  12
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  2-甲基环戊酮 、 甲胺 在 氢氧化钾 、 potassium phosphate 作用下， 以 水 为溶剂， 生成 2-甲基环戊醇 、 1-methylamino-2-methylcyclopentane
  参考文献：
  名称：

  Smirnov, Yu. D.; Tomilov, A. P., Journal of Organic Chemistry USSR (English Translation), 1992, vol. 28, # 1.1, p. 42 - 48

  摘要：

  DOI：

文献信息

• PYRROLOPYRIDINE INHIBITORS OF KINASES
  申请人：AbbVie Inc.

  公开号：US20140357616A1

  公开（公告）日：2014-12-04

  The present invention relates to compounds of formula (I) or pharmaceutical acceptable salts, wherein R 1a , R 1b , R 1c , X, and Y are defined in the description. The present invention relates also to compositions containing said compounds which are useful for inhibiting kinases such as Cdc7 and methods of treating diseases such as cancer.

  本发明涉及公式（I）的化合物或药学上可接受的盐，其中R1a，R1b，R1c，X和Y在说明中有定义。本发明还涉及含有所述化合物的组合物，该组合物对于抑制Cdc7等激酶以及治疗癌症等疾病具有用处的方法。
• METHOD FOR PRODUCING UNSATURATED ETHER COMPOUND
  申请人：Kyowa Hakko Chemical Co., Ltd.

  公开号：EP1876163A1

  公开（公告）日：2008-01-09

  The present invention provides a method for producing an unsaturated ether compound represented by general formula (2) below, the method comprising reacting an acetal represented by general formula (1) below in the presence of an aliphatic or aromatic sulfonic acid and an organic base having a total carbon number of 3 to 7. (In the formulae, R1, R2, and R3 may be the same or different and each represent substituted or unsubstituted alkyl, substituted or unsubstituted aryl, or substituted or unsubstituted aralkyl, or R1 and R2 form cycloalkyl together with the adjacent carbon atom.)

  本发明提供了一种生产下式(2)所代表的不饱和醚化合物的方法，该方法包括使下式(1)所代表的缩醛在脂肪族或芳香族磺酸和总碳数为3至7的有机碱存在下进行反应。(式中，R1、R2 和 R3 可以相同或不同，各自代表取代或未取代的烷基、取代或未取代的芳基、取代或未取代的芳烷基，或 R1 和 R2 与相邻碳原子一起形成环烷基)。
• Compounds useful for treating a Mannheimia haemolytica or Histophilus somni infection
  申请人：Intervet Inc.

  公开号：US11034650B2

  公开（公告）日：2021-06-15

  The present invention discloses compounds of formula (I) that are useful in the treatment of respiratory diseases of animals, especially Bovine or Swine Respiratory disease (BRD and SRD).

  本发明公开了可用于治疗动物呼吸道疾病，特别是牛或猪呼吸道疾病（BRD 和 SRD）的式（I）化合物。
• ISOPHTHALSÄUREDERIVATE
  申请人：Bayer HealthCare AG

  公开号：EP1572628B1

  公开（公告）日：2007-07-25
• USE OF SUBSTITUTED OXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI
  申请人：BASF SE

  公开号：US20170144980A1

  公开（公告）日：2017-05-25

  The present invention relates to the use of novel oxadiazoles of the formula I or an N-oxide and/or their agriculturally useful salts for controlling phytopathogenic fungi, or to a method for combating phytopathogenic harmful fungi, which process comprises treating the fungi or the materials, plants, the soil or seeds to be protected against fungal attack, with an effective amount of at least one compound of formula I or an N-oxide or an agriculturally acceptable salt thereof; and to agrochemical compositions comprising at least one such compound and to agrochemical compositions further comprising seeds.