4-[4-(2-tert-butoxycarbonylaminooxyacetoxyethyl)piperidin-1-yl]benzaldehyde | 848349-06-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: 4-[4-(2-tert-butoxycarbonylaminooxyacetoxyethyl)piperidin-1-yl]benzaldehyde
• 英文别名: 2-[1-(4-Formylphenyl)piperidin-4-yl]ethyl 2-[(2-methylpropan-2-yl)oxycarbonylamino]oxyacetate；2-[1-(4-formylphenyl)piperidin-4-yl]ethyl 2-[(2-methylpropan-2-yl)oxycarbonylamino]oxyacetate
• CAS: 848349-06-4
• 化学式: C₂₁H₃₀N₂O₆
• 分子量: 406.479
• InChiKey: PYMFAPLCWOHMPD-UHFFFAOYSA-N

物化性质

• 密度：
  1.165±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  29
• 可旋转键数：
  11
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  94.2
• 氢给体数：
  1
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  4-[4-(2-tert-butoxycarbonylaminooxyacetoxyethyl)piperidin-1-yl]benzaldehyde 、 肌氨酸 、 足球烯 以 甲苯 为溶剂， 反应 2.0h， 以32%的产率得到
  参考文献：
  名称：

  Versatile synthesis of oligosaccharide-containing fullerenes

  摘要：

  Oxylamine-functionalized fullerene derivatives have been synthesized in order to attach oligosaccharides to the fullerene surface by simple chemical ligation. This method greatly simplifies the synthetic process for a variety Of oligosaccharide-containing fullerenes without any complicated chemical modification. (C) 2004 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetasy.2004.11.039
• 作为产物：
  描述：

  4-哌啶乙醇 在 4-二甲氨基吡啶 、 sodium carbonate 、 盐酸-N-乙基-Nˊ-(3-二甲氨基丙基)碳二亚胺 作用下， 以 二氯甲烷 、 N,N-二甲基甲酰胺 为溶剂， 反应 1.5h， 生成 4-[4-(2-tert-butoxycarbonylaminooxyacetoxyethyl)piperidin-1-yl]benzaldehyde
  参考文献：
  名称：

  Versatile synthesis of oligosaccharide-containing fullerenes

  摘要：

  Oxylamine-functionalized fullerene derivatives have been synthesized in order to attach oligosaccharides to the fullerene surface by simple chemical ligation. This method greatly simplifies the synthetic process for a variety Of oligosaccharide-containing fullerenes without any complicated chemical modification. (C) 2004 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetasy.2004.11.039

文献信息

• Versatile synthesis of oligosaccharide-containing fullerenes
  作者：Shigeaki Abe、Hideki Moriyama、Kenichi Niikura、Fei Feng、Kenji Monde、Shin-Ichiro Nishimura

  DOI：10.1016/j.tetasy.2004.11.039

  日期：2005.1

  Oxylamine-functionalized fullerene derivatives have been synthesized in order to attach oligosaccharides to the fullerene surface by simple chemical ligation. This method greatly simplifies the synthetic process for a variety Of oligosaccharide-containing fullerenes without any complicated chemical modification. (C) 2004 Elsevier Ltd. All rights reserved.