3-Cyano-2-methyl-6-(1-naphthyl)-4-(2-thienyl)pyridine | 140885-65-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 3-Cyano-2-methyl-6-(1-naphthyl)-4-(2-thienyl)pyridine
• 英文别名: 2-Methyl-6-naphthalen-1-yl-4-thiophen-2-ylpyridine-3-carbonitrile
• CAS: 140885-65-0
• 化学式: C₂₁H₁₄N₂S
• 分子量: 326.422
• InChiKey: GGUYSDAGGPFAII-UHFFFAOYSA-N

物化性质

• 沸点：
  483.5±45.0 °C(Predicted)
• 密度：
  1.29±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.2
• 重原子数：
  24
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.05
• 拓扑面积：
  64.9
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  1-萘乙酮 在 sodium hydroxide 、 potassium tert-butylate 作用下， 以 乙醇 、 乙腈 为溶剂， 生成 3-Cyano-2-methyl-6-(1-naphthyl)-4-(2-thienyl)pyridine
  参考文献：
  名称：

  Synthesis and characterization of fluorescent 4,6-disubstituted-3-cyano-2-methylpyridines

  摘要：

  4,6-Disubstituted-3-cyano-2-methylpyridines, easily prepared by treating alpha,beta-unsaturated carbonyl compounds with beta-aminocrotononitrile in the presence of potassium tert-butoxide, have been found to show intense fluorescence in the region of 400-552 nm. 3-Cyano-4,6-bis(4-methoxyphenyl)-and 3-cyano-4,6-di(2-furyl)-2-methylpyridines show more intense fluorescence than 7-diethylamino-4-methylcoumarin. The 3-cyano group of pyridines increases the fluorescence intensities and improves photostabilities.

  DOI：

  10.1039/p29920000201

文献信息

• Synthesis and characterization of fluorescent 4,6-disubstituted-3-cyano-2-methylpyridines
  作者：Masaki Matsui、Akira Oji、Koichi Hiramatsu、Katsuyoshi Shibata、Hiroshige Muramatsu

  DOI：10.1039/p29920000201

  日期：——

  4,6-Disubstituted-3-cyano-2-methylpyridines, easily prepared by treating alpha,beta-unsaturated carbonyl compounds with beta-aminocrotononitrile in the presence of potassium tert-butoxide, have been found to show intense fluorescence in the region of 400-552 nm. 3-Cyano-4,6-bis(4-methoxyphenyl)-and 3-cyano-4,6-di(2-furyl)-2-methylpyridines show more intense fluorescence than 7-diethylamino-4-methylcoumarin. The 3-cyano group of pyridines increases the fluorescence intensities and improves photostabilities.