Quinolone carboxylic acid derivatives of formula (I) wherein Ar is an optionally substituted phenyl, pyridyl, or pyrimidinyl group and the substituent groups R1, R4, R10, R11, R19, and R20 are as defined in the specification, pharmaceutical compositions containing them, and methods of using them in treatment of hyperproliferative diseases such as cancer are disclosed and claimed.
公开和声明了式(I)的喹诺
酮羧酸衍
生物,其中Ar是可选择地取代的苯基、
吡啶基或
嘧啶基,取代基R1、R4、R10、R11、R19和R20如规范中定义,包含它们的药物组合物,以及在治疗癌症等高增殖性疾病中使用它们的方法。