N-Butyl-1-tetradecanamine | 19141-94-7

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N-Butyl-1-tetradecanamine
• 英文别名: N-butyltetradecan-1-amine
• CAS: 19141-94-7
• 化学式: C₁₈H₃₉N
• 分子量: 269.514
• InChiKey: UJKKZYQQIARLRJ-UHFFFAOYSA-N

物化性质

• 沸点：
  144 °C(Press: 0.975 Torr)
• 密度：
  0.805±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  7.7
• 重原子数：
  19
• 可旋转键数：
  16
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  12
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  正丁胺 、 溴代十四烷 反应 3.0h， 生成 N-Butyl-1-tetradecanamine
  参考文献：
  名称：

  Schade, W.; Beger, J.; Jacobi, R., Journal fur praktische Chemie (Leipzig 1954), 1983, vol. 325, # 3, p. 364 - 374

  摘要：

  DOI：

文献信息

• [EN] NOVEL INSULIN DERIVATIVES AND THE MEDICAL USES HEREOF<br/>[FR] NOUVEAUX DÉRIVÉS D'INSULINE ET LEURS UTILISATIONS MÉDICALES
  申请人：NOVO NORDISK AS

  公开号：WO2017032798A1

  公开（公告）日：2017-03-02

  The present invention is in the therapeutic fields of drugs for medical conditions relating to diabetes. More specifically the invention relates to novel acylated derivatives of human insulin analogues. The invention also provides pharmaceutical compositions comprising such insulin derivatives, and relates to the use of such derivatives for the treatment or prevention of medical conditions relating to diabetes.

  本发明涉及与糖尿病相关的医疗药物领域。更具体地，该发明涉及人类胰岛素类似物的新型酰化衍生物。该发明还提供了包含这种胰岛素衍生物的药物组合物，并涉及使用这些衍生物治疗或预防与糖尿病相关的医疗状况。
• A method for improving cold flow of hydrocarbon fuel oils
  申请人：NIPPON OIL AND FATS COMPANY, LIMITED

  公开号：EP0326356A1

  公开（公告）日：1989-08-02

  A method is disclosed for improving low temperature cold flow of fuel oils by using a cross-­linked ester compound consisting essentially of a nitrogen-containing compound having hydroxyl group, a straight chain fatty acid, and a cross-linking agent.

  本发明公开了一种使用交联酯化合物改善燃料油低温冷流动性的方法，交联酯化合物主要由具有羟基的含氮化合物、直链脂肪酸和交联剂组成。
• Novel perfluoropolyether derivatives, and lubricants and magnetic recording medium using the same
  申请人：SONY CORPORATION

  公开号：EP0519406A2

  公开（公告）日：1992-12-23

  Novel perfluoropolyether derivatives are described which are obtained from perfluoropolyethers having a carboxyl group at one or both ends and monoamines or diamines. The derivative is useful as a lubricant owing to its significantly improved lubricity. The lubricity is shown under severe high or low temperature and humidity conditions over a long term. The derivative is especially useful as a lubricant for magnetic recording mediums of the coating and metal thin film types.

  本文描述了新型全氟聚醚衍生物，该衍生物由一端或两端带有羧基的全氟聚醚和单胺或二胺制成。这种衍生物的润滑性能显著提高，可用作润滑剂。这种润滑性可在严酷的高温或低温和潮湿条件下长期保持。该衍生物特别适用于涂层型和金属薄膜型磁记录介质的润滑剂。
• Electron Transfer Reduction of Nitriles Using SmI₂–Et₃N–H₂O: Synthetic Utility and Mechanism
  作者：Michal Szostak、Brice Sautier、Malcolm Spain、David J. Procter

  DOI：10.1021/ol403668e

  日期：2014.2.21

  The first general reduction of nitriles to primary amines under single electron transfer conditions is demonstrated using SmI2 (Kagan's reagent) activated with Lewis bases. The reaction features excellent functional group tolerance and represents an attractive alternative to the use of pyrophoric alkali metal hydrides. Notably, the electron transfer from Sm(II) to CN functional groups generates imidoyl-type radicals from bench stable nitrile precursors.
• SCHADE, W.;BEGER, J.;JACOBI, R.;NEUMANN, R., J. PRAKT. CHEM., 1983, 325, N 3, 364-374
  作者：SCHADE, W.、BEGER, J.、JACOBI, R.、NEUMANN, R.

  DOI：——

  日期：——