1-chloro-octa-2,5-diyne | 99768-17-9

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 有机氯化物
• 英文名称: 1-chloro-octa-2,5-diyne
• 英文别名: 1-chloro-2,5-octadiyne；1-Chlor-octa-2,5-diin；1-Chloroocta-2,5-diyne
• CAS: 99768-17-9
• 化学式: C₈H₉Cl
• mdl: MFCD19233303
• 分子量: 140.612
• InChiKey: VVAYMXKKSNOQQW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  9
• 可旋转键数：
  0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  1-ethoxyethyl-1-(trimethysilyl)-1-propyn-3-yl ether 、 1-chloro-octa-2,5-diyne 在 1,3-二甲基-2-咪唑啉酮 、 copper(l) iodide 、 cesium fluoride 作用下， 反应 2.0h， 以64%的产率得到1-(1-ethoxy-ethoxy)-undeca-2,5,8-triyne
  参考文献：
  名称：

  基于1-（三甲基甲硅烷基）alk-1-yne制备1,4-跳过的二炔的新方法。

  摘要：

  [反应：参见正文]我们已经开发了一种新型TMS-炔烃与炔丙基卤之间的新型反应，该反应在氟化物源和催化量的碘化铜的存在下制备了1,4跳过的二炔，具有良好的收率和温和的反应。情况。我们已经表明，该反应对于锗和锡衍生物作为硅的替代品也非常有效。这种新方法可用于合成多不饱和脂肪酸。

  DOI：

  10.1021/ol0604670
• 作为产物：
  描述：

  1,4-二氯-2-丁炔 、 alkaline earth salt of/the/ methylsulfuric acid 在 乙醚 作用下， 生成 1-chloro-octa-2,5-diyne
  参考文献：
  名称：

  The Frontier Mountain meteorite trap (Antarctica)

  摘要：

  Abstract— The Frontier Mountain blue ice field is an important Antarctic meteorite trap which has yielded 472 meteorite specimens since its discovery in 1984. Remote sensing analyses and field campaigns from 1993 to 1999 have furnished new glaciological data on ice flow, ice thickness, bedrock topography, ice ablation and surface mass transport by wind, along with detailed descriptions of the field situation at the trap. This solid set of data combined with an updated meteorite distribution map and terrestrial ages available from literature allows us to better describe the nature of the concentration mechanism. In particular, we observe that the meteorite trap forms in a blue ice field (1) located upstream of an absolute and a shallow sub‐ice barriers; (2) characterized by compressive ice flow with horizontal velocities decreasing from 100 to <10 cm/year on approaching the obstacle; (3) undergoing mean ablation rates of 6.5 cm/year; (4) nourished by a limited snow accumulation zone extending ˜20 km upstream of the blue ice area. We also draw the following conclusions: (1) the origin of the meteorite trap can be explained according to the present‐day glaciological situation; (2) the meteorite concentration develops according to the general principles of the “ice flow model”; (3) the accumulation model can be described as “stagnant ice or slow‐moving ice against an absolute and submerged barriers”, according to the descriptive schemes present in literature; (4) the Frontier Mountain ice field is an effective trap for meteorites weighing more than ˜200 g; for smaller masses, the combination of wind and glacial drift may remove meteorites in less than a few tens of thousands of years; (5) although the activation age of the Frontier Mountain trap is not yet constrained, we infer that one of the most important findsites may be as old as 50 ka, predating the last glacial maximum.

  DOI：

  10.1111/j.1945-5100.2002.tb01105.x

文献信息

• The Frontier Mountain meteorite trap (Antarctica)
  作者：Luigi FOLCO、Alessandro CAPRA、Massimo CHIAPPINI、Màssimo FREZZOTTI、Marcello MELLINI、Ignazio Ezio TABACCO

  DOI：10.1111/j.1945-5100.2002.tb01105.x

  日期：2002.2

  Abstract— The Frontier Mountain blue ice field is an important Antarctic meteorite trap which has yielded 472 meteorite specimens since its discovery in 1984. Remote sensing analyses and field campaigns from 1993 to 1999 have furnished new glaciological data on ice flow, ice thickness, bedrock topography, ice ablation and surface mass transport by wind, along with detailed descriptions of the field situation at the trap. This solid set of data combined with an updated meteorite distribution map and terrestrial ages available from literature allows us to better describe the nature of the concentration mechanism. In particular, we observe that the meteorite trap forms in a blue ice field (1) located upstream of an absolute and a shallow sub‐ice barriers; (2) characterized by compressive ice flow with horizontal velocities decreasing from 100 to <10 cm/year on approaching the obstacle; (3) undergoing mean ablation rates of 6.5 cm/year; (4) nourished by a limited snow accumulation zone extending ˜20 km upstream of the blue ice area. We also draw the following conclusions: (1) the origin of the meteorite trap can be explained according to the present‐day glaciological situation; (2) the meteorite concentration develops according to the general principles of the “ice flow model”; (3) the accumulation model can be described as “stagnant ice or slow‐moving ice against an absolute and submerged barriers”, according to the descriptive schemes present in literature; (4) the Frontier Mountain ice field is an effective trap for meteorites weighing more than ˜200 g; for smaller masses, the combination of wind and glacial drift may remove meteorites in less than a few tens of thousands of years; (5) although the activation age of the Frontier Mountain trap is not yet constrained, we infer that one of the most important findsites may be as old as 50 ka, predating the last glacial maximum.
• New Method Based on 1-(Trimethysilyl)alk-1-yne To Prepare 1,4-Skipped Diynes
  作者：Florian Montel、Renaud Beaudegnies、Jilali Kessabi、Benjamin Martin、Eric Muller、Sebastian Wendeborn、Pierre M. J. Jung

  DOI：10.1021/ol0604670

  日期：2006.4.1

  of a fluoride source and a catalytic amount of copper iodide to prepare 1,4-skipped diynes with good yields and in mild conditions. We have shown that this reaction also works very well with germanium and tin derivatives as an alternative to silicon. This new method can be useful for the synthesis of polyunsaturated fatty acids.

  [反应：参见正文]我们已经开发了一种新型TMS-炔烃与炔丙基卤之间的新型反应，该反应在氟化物源和催化量的碘化铜的存在下制备了1,4跳过的二炔，具有良好的收率和温和的反应。情况。我们已经表明，该反应对于锗和锡衍生物作为硅的替代品也非常有效。这种新方法可用于合成多不饱和脂肪酸。