6-(6-amino-1H,3H-benzo[de]isoquinolin-2-yl)hexanoic acid | 946390-55-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 6-(6-amino-1H,3H-benzo[de]isoquinolin-2-yl)hexanoic acid
• 英文别名: 6-(6-Amino-1h,3h-benzo[de]isoquinolin-2-yl)-hexanoic acid；6-(6-amino-1,3-dihydrobenzo[de]isoquinolin-2-yl)hexanoic acid
• CAS: 946390-55-2
• 化学式: C₁₈H₂₂N₂O₂
• 分子量: 298.385
• InChiKey: WDMGECBLSVTUCP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.2
• 重原子数：
  22
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.39
• 拓扑面积：
  66.6
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  6-(6-amino-1,3-dioxo-1H,3H-benzo[de]isoquinolin-2-yl)-hexanoic acid 在 盐酸 、 汞 、 锌 作用下， 以 乙醇 为溶剂， 反应 0.5h， 生成 6-(6-amino-1H,3H-benzo[de]isoquinolin-2-yl)hexanoic acid
  参考文献：
  名称：

  Novel Fluorophores for Labeling of Nucleosides and Oligonucleotides

  摘要：

  Five novel fluorophores have been synthesized and their comparative fluorescence has been studied in different organic solvents and aqueous solutions of inorganic ions. Out of these, two highly sensitive fluorophores have been used to label phosphoramidites and oligodeoxyribonucleotides. The fluorescently labelled amidites and oligodeoxyribonucleotides showed good fluorescence signals.

  DOI：

  10.1080/15257770701547222

文献信息

• Novel Fluorophores for Labeling of Nucleosides and Oligonucleotides
  作者：Shipra Singh、Ramendra K. Singh

  DOI：10.1080/15257770701547222

  日期：2007.11.26

  Five novel fluorophores have been synthesized and their comparative fluorescence has been studied in different organic solvents and aqueous solutions of inorganic ions. Out of these, two highly sensitive fluorophores have been used to label phosphoramidites and oligodeoxyribonucleotides. The fluorescently labelled amidites and oligodeoxyribonucleotides showed good fluorescence signals.