1-Methyl-2-nitro-3-(oxolan-2-ylmethyl)guanidine

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 1-Methyl-2-nitro-3-(oxolan-2-ylmethyl)guanidine
• 英文别名: 1-methyl-2-nitro-3-(oxolan-2-ylmethyl)guanidine
• 化学式: C7H14N4O3
• 分子量: 202.21
• InChiKey: JYRJNCSOPIJOJK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  14
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  91.5
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• Furanyl insecticide
  申请人：MITSUI TOATSU CHEMICALS, Inc.

  公开号：EP0649845A1

  公开（公告）日：1995-04-26

  The present invention relates to novel (tetrahydro-3-furanyl)methylamino derivatives of the following formula (1): where X₁, X₂, X₃, X₄, X₅, X₆ and X₇ represent each a hydrogen atom or an alkyl group having from 1 to 4 carbon atoms, R₁ represents a hydrogen atom, an alkyl group having from 1 to 5 carbon atoms, an alkenyl group having 3 carbon atoms, a benzyl group, an alkoxyalkyl group having from 2 to 4 carbon atoms (in its whole group), an alkyloxycarbonyl group having from 1 to 3 carbon atoms in its alkyloxy portion, a phenoxy carbonyl group, an alkylcarbonyl group having from 1 to 6 carbon atoms in its alkyl portion, an alkenylcarbonyl group having from 2 to 3 carbon atoms in its alkenyl portion, a cycloalkylcarbonyl group having from 3 to 6 carbon atoms in its cycloalkyl portion, a benzoyl group, a benzoyl group substituted by 1 to 3 alkyl group(s) having from 1 to 4 carbon atoms, a benzoyl group substituted by 1 to 3 halogen atom(s), a 2-furanylcarbonyl group or an N,N-dimethylcarbamoyl group; R₂ represents a hydrogen atom, an amino group, a methyl group, an alkylamino group having from 1 to 5 carbon atoms, a di-substituted alkylamino group having from 2 to 5 carbon atoms (in its whole group), a 1-pyrrolidinyl group, an alkenylamino group having 3 carbon atoms, an alkynylamino group having 3 carbon atoms, a methoxyamino group, an alkoxyalkylamino group having from 2 to 4 carbon atoms (in its whole group), a methylthio group, or -N(Y₁)Y₂ (where Y₁ represents an alkyloxycarbonyl group having from 1 to 3 carbon atoms in its alkyloxy portion, a phenoxycarbonyl group, an alkylcarbonyl group having from 1 to 6 carbon atoms in its alkyl portion, an alkenylcarbonyl group having from 2 to 3 carbon atoms in its alkenyl portion, a cycloalkylcarbonyl group having from 3 to 6 carbon atoms in its cycloalkyl group, a benzoyl group, a benzoyl group substituted by 1 to 3 alkyl group(s) having form 1 to 4 carbon atoms, a benzoyl group substituted by 1 to 3 halogen atom(s), a 2-furanylcarbonyl group, a an N,N-dimethylcarbamoyl group, a (tetrahydro-3-furanyl)methyl group or a benzyl group, and Y₂ represents a hydrogen atom or an alkyl group having from 1 to 5 carbon atoms); and Z represents =N-NO₂, =CH-NO₂ or =N-CN, and insecticides containing the derivatives as an effective ingredient.

  本发明涉及下式（1）的新型（四氢-3-呋喃基）甲氨基衍生物： 其中 X₁、X₂、X₃、X₄、X₅、X₆ 和 X₇ 分别代表氢原子或具有 1 至 4 个碳原子的烷基，R₁ 代表氢原子、具有 1 至 5 个碳原子的烷基具有 3 个碳原子的烯基、苄基、具有 2 至 4 个碳原子（全基）的烷氧基烷基、其烷氧基部分具有 1 至 3 个碳原子的烷氧羰基、苯氧基羰基、烷基部分含有 1 至 6 个碳原子的烷基羰基、烯基部分含有 2 至 3 个碳原子的烯基羰基、环烷基部分含有 3 至 6 个碳原子的环烷基羰基、苯甲酰基、被 1 至 3 个含有 1 至 4 个碳原子的烷基取代的苯甲酰基、被 1 至 3 个卤素原子取代的苯甲酰基、2-呋喃基羰基或 N,N-二甲基氨基甲酰基；R₂ 代表氢原子、氨基、甲基、具有 1 至 5 个碳原子的烷基氨基、具有 2 至 5 个碳原子（全基）的二取代烷基氨基、1-吡咯烷基、具有 3 个碳原子的烯基氨基、具有 3 个碳原子的烷基氨基、甲氧基氨基、具有 2 至 4 个碳原子（全基）的烷氧基烷基氨基、甲硫基或 -N(Y₁)Y₂（其中 Y₁ 代表烷氧基部分具有 1 至 3 个碳原子的烷氧基羰基、苯氧基羰基、在其烷基部分中具有 1 至 6 个碳原子的烷基羰基、在其烯基部分中具有 2 至 3 个碳原子的烯基羰基、在其环烷基中具有 3 至 6 个碳原子的环烷基羰基、苯甲酰基、被 1 至 3 个具有 1 至 4 个碳原子的烷基取代的苯甲酰基、被 1 至 3 个卤素原子取代的苯甲酰基、2-呋喃基羰基、N,N-二甲基氨基甲酰基、（四氢-3-呋喃基）甲基或苄基，且 Y₂ 代表氢原子或具有 1 至 5 个碳原子的烷基；和 Z 代表 =N-NO₂、=CH-NO₂ 或 =N-CN，以及含有这些衍生物作为有效成分的杀虫剂。
• Method for controlling ectoparasites
  申请人：Sumitomo Chemical Company, Limited

  公开号：EP0966961A1

  公开（公告）日：1999-12-29

  A method for controlling ectoparasites systemically through host animal blood which comprises applying at least one selected from the neonocotinoid compounds defined in the specification to the host animal.

  一种通过宿主动物血液系统控制体外寄生虫的方法，包括向宿主动物施用至少一种选自说明书中定义的新烟碱类化合物。
• Gelled bait
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：US20040253288A1

  公开（公告）日：2004-12-16

  An effective gelled poison bait is provided for the control of such objective insect as cockroaches, wherein the bait comprises 1-methyl-2-nitro-3-[(tetrahydrofuryl)methyl]guanidine, carrageenan, polyvinyl alcohol, at least one selected from fats and fatty oils and water.

  提供了一种有效的胶状毒饵，用于控制蟑螂等目标昆虫，其中毒饵包括 1-甲基-2-硝基-3-[（四氢糠基）甲基]胍、卡拉胶、聚乙烯醇、至少一种选自脂肪和脂肪油的物质以及水。
• Process for the preparation of nitroguanidine derivatives starting from 2-nitroimino-hexahydro-1,3,5-triazines in the presence of ammonia, primary or secondary amine
  申请人：MITSUI CHEMICALS, INC.

  公开号：EP0869120B1

  公开（公告）日：2005-07-20
• Ectoparasite controlling agent for animals
  申请人：Sumitomo Chemical Company, Limited

  公开号：EP0976328B1

  公开（公告）日：2004-10-06