甲基-(3-戊基)胺盐酸盐

• 分子结构分类: 有机化合物 - 有机氮化合物
• 中文名称: 甲基-(3-戊基)胺盐酸盐
• 英文名称: hydron;N-methylpentan-3-amine;chloride
• 化学式: C6H16ClN
• mdl: MFCD08689639
• 分子量: 137.65
• InChiKey: VTOBVEWRGMUFJJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.63
• 重原子数：
  8
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  12
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• PYRAZOLOTHIAZOLE COMPOUND AND MEDICINE
  申请人：Nippon Shinyaku Co., Ltd.

  公开号：EP3190116A1

  公开（公告）日：2017-07-12

  The invention provides a pyrazolothiazole compound of the formula [I], or a pharmaceutically acceptable salt thereof: The compound of the invention has JAK1 inhibitory activity, and thus, immunosuppressive effect, anti-inflammatory effect and anti-proliferative effect, and is useful in the treatment of the diseases, for example, rheumatoid arthritis, inflammatory bowel disease, psoriasis and vasculitis, bronchial asthma, chronic obstructive pulmonary disease and eosinophilic sinusitis, nasal polyp.

  本发明提供了一种式[I]的吡唑噻唑化合物或其药学上可接受的盐： 本发明的化合物具有 JAK1 抑制活性，因此具有免疫抑制作用、抗炎作用和抗增殖作用，可用于治疗疾病，例如类风湿性关节炎、炎症性肠病、银屑病和血管炎、支气管哮喘、慢性阻塞性肺病和嗜酸性鼻窦炎、鼻息肉。
• PYRAZOLOTHIAZOLE COMPOUND AND MEDICINE COMPRISING SAME
  申请人：Nippon Shinyaku Co., Ltd.

  公开号：EP3190116B1

  公开（公告）日：2020-08-05
• POLYMERASE CHAIN REACTION COMPOSITION COMPRISING AMINES
  申请人：THERMO FISHER SCIENTIFIC BALTICS UAB

  公开号：EP3728633A1

  公开（公告）日：2020-10-28
• CHEMICAL ADDITIVES AND SURFACTANT COMBINATIONS FOR FAVORABLE WETTABILITY ALTERATION AND IMPROVED HYDROCARBON RECOVERY FACTORS
  申请人：Alchemy Sciences, Inc.

  公开号：US20200131431A1

  公开（公告）日：2020-04-30

  A modified treatment fluid includes a first surfactant, wherein the first surfactant is nonionic, cationic, anionic, zwitterionic, or a combination thereof and a wettability altering additive (WEA) that includes an organic salt, an inorganic salt, urea, a urea derivative, a carbamate, ammonia, an amine, a glycol, a glycol ether, an amide, an aldehyde, or a combination thereof. The modified treatment fluid further includes a treatment fluid.
• US9937176B2
  申请人：——

  公开号：US9937176B2

  公开（公告）日：2018-04-10