4-(naphthalen-1-yl)phthalazin-1(2H)-one | 57835-94-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂萘
• 英文名称: 4-(naphthalen-1-yl)phthalazin-1(2H)-one
• 英文别名: 4-α-naphthylphthalaz-1-one；4-(1-naphthyl)phthalaz-1-one；4-[1]naphthyl-2H-phthalazin-1-one；4-[1]Naphthyl-2H-phthalazin-1-on；4-(1-Naphthyl)phthalazin-1(2h)-one；4-naphthalen-1-yl-2H-phthalazin-1-one
• CAS: 57835-94-6
• 化学式: C₁₈H₁₂N₂O
• 分子量: 272.306
• InChiKey: KXFRSVCWEHBKQT-UHFFFAOYSA-N

物化性质

• 熔点：
  252-253 °C
• 密度：
  1.26±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  21
• 可旋转键数：
  1
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  41.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  氨基邻苯二甲胺 以 乙醚 、 乙醇 、 苯 为溶剂， 反应 7.0h， 生成 4-(naphthalen-1-yl)phthalazin-1(2H)-one
  参考文献：
  名称：

  Ismail, M. Fekry; El-Bassiouny, F. A.; Enayat, E. I., Journal fur praktische Chemie (Leipzig 1954), 1985, vol. 327, # 2, p. 177 - 182

  摘要：

  DOI：

文献信息

• Palladium-Catalyzed Acylation Reactions: A One-Pot Diversified Synthesis of Phthalazines, Phthalazinones and Benzoxazinones
  作者：Basuli Suchand、Gedu Satyanarayana

  DOI：10.1002/ejoc.201800159

  日期：2018.5.24

  proceeds through [Pd]‐catalyzed acylation and nucleophilic cyclocondensation with dinucleophilic reagents. This process was based on direct coupling with simple bench‐top aldehydes without the assistance of directing group and without activating the carbonyl group. The process is highly advantageous because it employs simple nitrogen‐based nucleophiles, and non‐toxic and readily accessible aldehydes as the

  提出了一种用于酞嗪、酞嗪酮和苯并恶嗪酮多样化合成的连续单锅策略。该策略通过 [Pd] 催化的酰化和与双亲核试剂的亲核环缩合反应进行。该过程基于与简单的台式醛直接偶联，没有导向基团的帮助，也没有活化羰基。该方法非常有利，因为它使用简单的氮基亲核试剂和无毒且易于获得的醛作为羰基来源。最重要的是，该策略被应用于 PDE-4 抑制剂的一锅合成。
• New convenient one-step synthesis of 4-arylphthalaz-1 -ones
  作者：M. Fekry Ismail、F.A. El-Bassiouny、H.A. Younes

  DOI：10.1016/s0040-4020(01)91312-2

  日期：1984.1

  hitherto unknown reaction of N-aminophthalimide (1) with aromatic hydrocarbons under Friedel-Crafts conditions. The reaction of N-aminophthalimide with Grignard reagents presents another convenient method for the synthesis of 4-alkyl or 4-arylphthalaz-1-ones.

  4-芳基邻苯二甲-1-酮（2a–e）是由迄今为止尚未发现的N-氨基邻苯二甲酰亚胺（1）与芳烃在Friedel-Crafts条件下的反应制得的。N-氨基邻苯二甲酰亚胺与格氏试剂的反应提供了另一种方便的合成4-烷基或4-芳基邻苯二氮-1-酮的方法。
• Method for producing grains of aliphatic acid silver salt and thermally processed image recording material
  申请人：——

  公开号：US20010018170A1

  公开（公告）日：2001-08-30

  A method for producing grains of aliphatic acid silver salt by mixing a solution containing silver ions and a solution of aliphatic acid alkali metal salt to attain reaction of them, wherein (1) 95-100% of the total molar number to be added of the aliphatic acid alkali metal salt is added under a condition that dilution factor of the solution of aliphatic acid alkali metal salt becomes 10-fold or higher at 1 second after the addition, (2) 95-100% of the total amount to be added of silver in the solution containing silver ions is added under a condition that dilution factor of the solution containing silver ions becomes 20-fold or higher at 1 second after the addition, and (3) 50-100% of the total amount to be added of the solution of aliphatic acid alkali metal salt is added simultaneously with the solution containing silver ions. According to the present invention, there is provided a method for producing grains of aliphatic acid silver salt, which show excellent fog prevention ability, in addition, excellent fog prevention ability even after time lapse, when used in a thermally processed image recording material.

  本发明提供了一种制备脂肪族酸银盐颗粒的方法，包括将含有银离子的溶液和脂肪族酸碱金属盐的溶液混合以使它们反应，其中（1）脂肪族酸碱金属盐的总摩尔数的95-100％在加入后1秒钟时，脂肪族酸碱金属盐的稀释因子变为10倍或更高，（2）所含银离子的溶液中总添加量的95-100％在加入后1秒钟时，银离子溶液的稀释因子变为20倍或更高，（3）脂肪族酸碱金属盐溶液的总添加量的50-100％同时与含银离子的溶液一起加入。该发明提供了一种制备脂肪族酸银盐颗粒的方法，该颗粒具有出色的防雾能力，并且即使在时间流逝后，当用于热处理的图像记录材料时，仍具有出色的防雾能力。
• Bisphenol-phosphorous compound complex and thermally processed image recording material utilizing the same
  申请人：——

  公开号：US20020009683A1

  公开（公告）日：2002-01-24

  Bisphenol-phosphorus compound complexes represented by the following general formula (1) are disclosed (R 1 to R 4 represent hydrogen atom or a group that can be a substituent on a benzene ring; L represents —S— group or a —CHR 5 — group where R 5 represents hydrogen atom or an alkyl group; and R 6 to R 8 represent an alkyl group, an aryl group, a heterocyclic group etc.). The present invention provides reducing agents that can realize thermally processed image recording materials that can provide sufficient image density at a practical reaction temperature (specifically 100-140° C.) and within a practical reaction time (specifically 1-30 seconds), and can sufficiently suppress the coloration of white portions when the materials are stored in a dark place after the development.

  本发明揭示了以下一般式（1）所代表的双酚-磷化合物配合物（其中R1至R4代表氢原子或苯环上可取代基团；L代表—S—基团或—CHR5—基团，其中R5代表氢原子或烷基；R6至R8代表烷基、芳基、杂环基等）。本发明提供了还原剂，可以实现在实际反应温度（具体为100-140℃）和实际反应时间（具体为1-30秒）内提供足够的图像密度的热处理图像记录材料，并且在开发后在暗处存储材料时可以充分抑制白色部分的着色。
• Bisphenol-phosphorus compound complex and thermally processed image recording material utilizing the same
  申请人：FUJI PHOTO FILM CO., LTD.

  公开号：US20030045738A1

  公开（公告）日：2003-03-06

  Bisphenol-phosphorus compound complexes represented by the following general formula (1) are disclosed (R 1 to R 4 represent hydrogen atom or a group that can be a substituent on a benzene ring; L represents —S— group or a —CHR 5 — group where R 5 represents hydrogen atom or an alkyl group; and R 6 to R 8 represent an alkyl group, an aryl group, a heterocyclic group etc.). The present invention provides reducing agents that can realize thermally processed image recording materials that can provide sufficient image density at a practical reaction temperature (specifically 100-140° C.) and within a practical reaction time (specifically 1-30 seconds), and can sufficiently suppress the coloration of white portions when the materials are stored in a dark place after the development.

  本发明揭示了以下一般式（1）所代表的双酚-磷化合物配合物（其中R1至R4代表氢原子或苯环上可以作为取代基的基团；L代表—S—基团或—CHR5—基团，其中R5代表氢原子或烷基；而R6至R8代表烷基、芳基、杂环基等）。本发明提供了还原剂，可以实现在实际反应温度（具体为100-140℃）和实际反应时间（具体为1-30秒）内提供足够的图像密度的热处理图像记录材料，并且在开发后在黑暗处存储时足够抑制白色部分的着色。