3-Cycloheptylaminopropan-1-ol | 55611-64-8

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 3-Cycloheptylaminopropan-1-ol
• 英文别名: 3-(Cycloheptylamino)propan-1-OL
• CAS: 55611-64-8
• 化学式: C₁₀H₂₁NO
• mdl: MFCD11162924
• 分子量: 171.283
• InChiKey: OXYJOLIHFRNKIB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  12
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  32.3
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  3-Cycloheptylaminopropan-1-ol 、 肉桂基氯 以65%的产率得到
  参考文献：
  名称：

  FELFOELDI K.; LASZLAVIK M.; BARTOK M.; KARPATI E., ACTA PHYS. ET CHEM. SZEGED, 1980, 26, NO 3-4, 171-176

  摘要：

  DOI：
• 作为产物：
  描述：

  3-氨基-1-丙醇 、 环庚酮 以73%的产率得到
  参考文献：
  名称：

  FELFOELDI K.; LASZLAVIK M.; BARTOK M.; KARPATI E., ACTA PHYS. ET CHEM. SZEGED, 1980, 26, NO 3-4, 171-176

  摘要：

  DOI：

文献信息

• Pyrrolo[2,3-d]pyrimidine compounds
  申请人：——

  公开号：US20020019526A1

  公开（公告）日：2002-02-14

  A compound of the formula 1 wherein R 1 , R 2 and R 3 are as defined above, which are inhibitors of the enzyme protein tyrosine kinases such as Janus Kinase 3 and as such are useful therapy as immunosuppressive agents for organ transplants, lupus, multiple sclerosis, rheumatoid arthritis, psoriasis, Type I diabetes and complications from diabetes, cancer, asthma, atopic dermatitis, autoimmune thyroid disorders, ulcerative colitis, Crohn's disease, Alzheimer's disease, Leukemia and other autoimmune diseases.

  一种化合物的结构式，其中R1、R2和R3如上所定义，它们是蛋白酪氨酸激酶的抑制剂，如Janus激酶3，因此可作为免疫抑制剂用于器官移植、狼疮、多发性硬化、类风湿性关节炎、牛皮癣、1型糖尿病和糖尿病并发症、癌症、哮喘、特应性皮炎、自身免疫性甲状腺疾病、溃疡性结肠炎、克罗恩病、阿尔茨海默病、白血病和其他自身免疫疾病的治疗。
• Pyrrolo [2,3-D] pyrimidine compounds
  申请人：Pfizer Inc.

  公开号：US20030212273A1

  公开（公告）日：2003-11-13

  A compound of the formula 1 wherein R 1 , R 2 and R 3 are as defined above, which are inhibitors of the enzyme protein tyrosine kinases such as Janus Kinase 3 and as such are useful therapy as immunosuppressive agents for organ transplants, lupus, multiple sclerosis, rheumatoid arthritis, psoriasis, Type I diabetes and complications from diabetes, cancer, asthma, atopic dermatitis, autoimmune thyroid disorders, ulcerative colitis, Crohn's disease, Alzheimer's disease, Leukemia and other autoimmune diseases.

  化合物的公式为1，其中R1，R2和R3的定义如上所述，它们是蛋白酪氨酸激酶的抑制剂，例如Janus Kinase 3，并且作为免疫抑制剂用于器官移植，狼疮，多发性硬化症，类风湿性关节炎，牛皮癣，1型糖尿病和糖尿病并发症，癌症，哮喘，特应性皮炎，自身免疫性甲状腺疾病，溃疡性结肠炎，克罗恩病，阿尔茨海默病，白血病和其他自身免疫性疾病的有用治疗方法。
• Acid gas absorbent, acid gas removal method and acid gas removal device
  申请人：Kabushiki Kaisha Toshiba

  公开号：EP2468385A2

  公开（公告）日：2012-06-27

  An acid gas absorbent of which recovery amount of acid gas such as carbon dioxide is high, and an acid gas removal device and an acid gas removal method using the acid gas absorbent are provided. The acid gas absorbent of the embodiment comprising at least one type of tertiary amine compound represented by the following general formula (1). (In the above-stated formula (1), either one of the R1, R2 represents a substituted or non-substituted alkyl group of which carbon number is 2 to 5, and the other one represents a substituted or non-substituted alkyl group of which carbon number is 1 to 5. The R3 represents a methyl group or an ethyl group, and the R4 represents a hydroxyalkyl group. The R1, R2 may either be the same or different, and they may be coupled to form a cyclic structure.) The acid gas aborbent may also be a secondary amine.

  本发明提供了一种二氧化碳等酸性气体回收量高的酸性气体吸收剂，以及使用该酸性气体吸收剂的酸性气体去除装置和酸性气体去除方法。本实施例中的酸性气体吸收剂包含至少一种由以下通式（1）表示的叔胺化合物。 (在上述式（1）中，R1、R2 中的任一个代表碳数为 2 至 5 的取代或非取代烷基，另一个代表碳数为 1 至 5 的取代或非取代烷基。R3 代表甲基或乙基，R4 代表羟烷基。R1、R2 既可以相同，也可以不同，它们可以联接形成环状结构）。 酸性气体吸收剂也可以是仲胺。
• PYRROLO 2,3-d]PYRIMIDINE COMPOUNDS
  申请人：Pfizer Products Inc.

  公开号：EP1087970B1

  公开（公告）日：2004-04-28
• ACID GAS ABSORBENT, ACID GAS REMOVAL METHOD, AND ACID GAS REMOVAL DEVICE
  申请人：MURAI Shinji

  公开号：US20120161071A1

  公开（公告）日：2012-06-28

  An acid gas absorbent of which recovery amount of acid gas such as carbon dioxide is high, and an acid gas removal device and an acid gas removal method using the acid gas absorbent are provided. The acid gas absorbent of the embodiment comprising at least one type of tertiary amine compound represented by the following general formula (1). (In the above-stated formula (1), either one of the R 1 , R 2 represents a substituted or non-substituted alkyl group of which carbon number is 2 to 5, and the other one represents a substituted or non-substituted alkyl group of which carbon number is 1 to 5. The R 3 represents a methyl group or an ethyl group, and the R 4 represents a hydroxyalkyl group. The R 1 , R 2 may either be the same or different, and they may be coupled to form a cyclic structure.)