24-去甲石胆酸 | 15238-52-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 中文名称: 24-去甲石胆酸
• 英文名称: 3β-hydroxy-24-nor-5α-cholan-23-oic acid
• 英文别名: 3β-Hydroxy-24-nor-5α-cholan-23-saeure；3β-Hydroxy-24-nor-5α-cholansaeure-(23)；24-Norlithocholic acid；(3R)-3-[(3S,5S,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]butanoic acid
• CAS: 15238-52-5
• 化学式: C₂₃H₃₈O₃
• 分子量: 362.553
• InChiKey: BIGINLZPDKMEPQ-ZZAVNFEKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.9
• 重原子数：
  26
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.96
• 拓扑面积：
  57.5
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  24-去甲石胆酸 在 重氮甲烷 、 甲醇 、 乙醚 作用下， 生成 methyl 3β-hydroxy-24-nor-5α-cholan-23-oate
  参考文献：
  名称：

  Effects of Engine Speed and Accessory Load on Idling Emissions from Heavy-Duty Diesel Truck Engines

  摘要：

  A nontrivial portion of. heavy-duty vehicle emissions of NOx and particulate matter (PM) occurs during idling. Regulators and the environmental community are interested in curtailing truck idling emissions, but current emissions models do not characterize them accurately, and little quantitative data exist to evaluate the relative effectiveness of various policies. The objectives of this study were to quantify the effect of accessory loading and engine speed on idling emissions from a properly functioning, modern, heavy-duty diesel truck and to compare these results with data from earlier model year vehicles. It was found that emissions during idling varied greatly as. a function of engine model year, engine speed,and accessory load conditions. For the 1999 model year Class 8 truck tested, raising the engine speed from 600 to 1050 rpm and turning on the air conditioning resulted in a 2.5-fold increase in NOx emissions in grams per hour, a 2-fold increase in CO2 emissions, and a 5-fold increase in CO emissions while idling. On a grams per gallon fuel basis, NOx emissions while idling were approximately twice as high as those at 55 mph. The CO2 emissions at the two conditions were closer. The NOx emissions from the 1999 truck while idling with air conditioning running were slightly more than those of two 1990 model year trucks under equivalent conditions, and the hydrocarbon (HC) and CO emissions were significantly lower. It was found that the NOx emissions used in the California Air Resources Board's (CARB) EMFAC2000 and the U.S. Environmental Protection Agency's (EPA) MOBILE5b emissions inventory models were lower than those measured in all of the idling conditions tested on the 1999 truck.

  DOI：

  10.1080/10473289.2002.10470838
• 作为产物：
  描述：

  3β-acetoxy-24-nor-5α-cholanoic acid-(23) 在 氢氧化钾 作用下， 生成 24-去甲石胆酸
  参考文献：
  名称：

  Ercoli, 1944, vol. 23, p. 149,151

  摘要：

  DOI：

文献信息

• Dirscherl, Hoppe-Seyler's Zeitschrift fur Physiologische Chemie, 1935, vol. 237, p. 268,271
  作者：Dirscherl

  DOI：——

  日期：——
• Mitsui, Nippon Nogeikagaku Kaishi, 1939, vol. 15, p. 795,798, 801
  作者：Mitsui

  DOI：——

  日期：——
• �ber Steroide und Sexualhormone. (86. Mitteilung). �ber die Hydrierungsprodukte der ?5,6;20,22-3?-Oxy-nor-choladiens�ure
  作者：Pl. A. Plattner、J. Pataki

  DOI：10.1002/hlca.19430260427

  日期：1943.6.15
• Ercoli; de Ruggieri, Il Farmaco, scienza e tecnica, 1951, vol. 6, p. 688,691
  作者：Ercoli、de Ruggieri

  DOI：——

  日期：——
• Effects of Engine Speed and Accessory Load on Idling Emissions from Heavy-Duty Diesel Truck Engines
  作者：Christie-Joy Brodrick、Harry A. Dwyer、Mohammad Farshchi、D. Bruce Harris、Foy G. King

  DOI：10.1080/10473289.2002.10470838

  日期：2002.9

  A nontrivial portion of. heavy-duty vehicle emissions of NOx and particulate matter (PM) occurs during idling. Regulators and the environmental community are interested in curtailing truck idling emissions, but current emissions models do not characterize them accurately, and little quantitative data exist to evaluate the relative effectiveness of various policies. The objectives of this study were to quantify the effect of accessory loading and engine speed on idling emissions from a properly functioning, modern, heavy-duty diesel truck and to compare these results with data from earlier model year vehicles. It was found that emissions during idling varied greatly as. a function of engine model year, engine speed,and accessory load conditions. For the 1999 model year Class 8 truck tested, raising the engine speed from 600 to 1050 rpm and turning on the air conditioning resulted in a 2.5-fold increase in NOx emissions in grams per hour, a 2-fold increase in CO2 emissions, and a 5-fold increase in CO emissions while idling. On a grams per gallon fuel basis, NOx emissions while idling were approximately twice as high as those at 55 mph. The CO2 emissions at the two conditions were closer. The NOx emissions from the 1999 truck while idling with air conditioning running were slightly more than those of two 1990 model year trucks under equivalent conditions, and the hydrocarbon (HC) and CO emissions were significantly lower. It was found that the NOx emissions used in the California Air Resources Board's (CARB) EMFAC2000 and the U.S. Environmental Protection Agency's (EPA) MOBILE5b emissions inventory models were lower than those measured in all of the idling conditions tested on the 1999 truck.