(p-Me2NC6H4)2Sn(NMe2)2 | 880475-50-3

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: (p-Me2NC6H4)2Sn(NMe2)2
• CAS: 880475-50-3
• 化学式: C₂₀H₃₂N₄Sn
• 分子量: 447.211
• InChiKey: HUEWCNIIINZGGR-UHFFFAOYSA-N

物化性质

• 沸点：
  465.8±55.0 °C(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.58
• 重原子数：
  25
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  8.5
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  (p-Me2NC6H4)2Sn(NMe2)2 、 (3S,6S)-3-isopropyl-6-methylmorpholine-2,5-dione 以 苯 为溶剂， 以62%的产率得到[(p-Me2NC6H4)2Sn(μ,η3-OCH(Me)CONCH(i-Pr)CONMe2)]2
  参考文献：
  名称：

  关于各种金属催化剂对吗啉-2,5-二酮衍生物进行开环聚合反应的评论，以及表征涉及R2SnX2的反应中形成的产物的特征，其中X = OPr（i）和NMe2，R = Bu（n），Ph和p-Me2NC6H4。

  摘要：

  （3S，6S）-3-异丙基-6-甲基吗啉-2,5-二酮（1）和（3S，6S）-3,6-二甲基吗啉-2,5-二酮（2）如果不与丙交酯常用的金属催化剂前体以及辛酸锡（II）进行开环聚合反应，则只能得到低分子量的低聚物。与R2SnX2化合物的反应（其中R = Ph，Bu（n）和p-Me2NC6H4和X = OPr（i）或NMe2）显示确实发生了吗啉-2,5-二酮的开环，但聚合反应终止了通过形成动力学惰性的产物，例如{Ph2Sn [mu，eta（3）-OCH（Me）CONCH（Pr（i））COOPr（i）]} 2（3）和{[Bu（n）） 2Sn [mu，eta（3）-OCH（Me）CONCH（Me）CONMe2]} 2（4），除去HX。Ph3SnOPr（i）与吗啉2可逆反应，通过1 H NMR光谱分析甲苯-d8中的5-二酮，同时（Bu（n））3SnNMe2通过开环反应得到（Bu（n））3SnOCH

  DOI：

  10.1039/b510580c
• 作为产物：
  描述：

  p-Sn{C6H4N(CH3)2}4 以 甲苯 、 苯 为溶剂， 生成 (p-Me2NC6H4)2Sn(NMe2)2
  参考文献：
  名称：

  Ring-opening polymerization of l-lactide by organotin(IV)alkoxides, R2Sn(OPri)2: Estimation of the activation parameters

  摘要：

  The ring-opening polymerization of L-lactide, L-LA, to give poly-L-lactide by R2Sn(OPri)(2) compounds, where R = Bu-n and p-XC6H4 (X = CF3, F, H, Me and OMe) has been studied in benzene over a temperature range. There is a relatively small variation in Delta H not equal as a function of R with all the values falling within the range 11 +/- 2 kcal mol(-1). The entropy of activation, Delta S not equal, is consistently large and negative, -50 +/- 5 eu, supporting the view that the ring-opening event, the enchainment step involves a highly ordered transition state. The crystal and molecular structures of the compounds Ph2Sn(OPri)(2), (p-FC6H4)(2)Sn(OPri)(2) and (p-Me2NC6H4)(3)SnOPri are also reported. While the latter compound is monomeric in the solid state the former are both dimeric with a pair of bridging OPri ligands. (c) 2007 Published by Elsevier Ltd.

  DOI：

  10.1016/j.poly.2007.06.002

文献信息

• Ring-opening polymerization of l-lactide by organotin(IV)alkoxides, R2Sn(OPri)2: Estimation of the activation parameters
  作者：Malcolm H. Chisholm、Judith C. Gallucci、Clemens Krempner

  DOI：10.1016/j.poly.2007.06.002

  日期：2007.9

  The ring-opening polymerization of L-lactide, L-LA, to give poly-L-lactide by R2Sn(OPri)(2) compounds, where R = Bu-n and p-XC6H4 (X = CF3, F, H, Me and OMe) has been studied in benzene over a temperature range. There is a relatively small variation in Delta H not equal as a function of R with all the values falling within the range 11 +/- 2 kcal mol(-1). The entropy of activation, Delta S not equal, is consistently large and negative, -50 +/- 5 eu, supporting the view that the ring-opening event, the enchainment step involves a highly ordered transition state. The crystal and molecular structures of the compounds Ph2Sn(OPri)(2), (p-FC6H4)(2)Sn(OPri)(2) and (p-Me2NC6H4)(3)SnOPri are also reported. While the latter compound is monomeric in the solid state the former are both dimeric with a pair of bridging OPri ligands. (c) 2007 Published by Elsevier Ltd.
• Comments on the ring-opening polymerization of morpholine-2,5-dione derivatives by various metal catalysts and characterization of the products formed in the reactions involving R₂SnX₂, where X = OPrⁱand NMe₂and R = Buⁿ, Ph and p-Me₂NC₆H₄
  作者：M. H. Chisholm、J. Galucci、C. Krempner、C. Wiggenhorn

  DOI：10.1039/b510580c

  日期：——

  (2), do not enter into ring-opening polymerization reactions with metal catalyst precursors commonly employed for lactides, and with Sn(II) octanoate, only low molecular weight oligomers are obtained. Reactions with R2SnX2 compounds, where R = Ph, Bu(n) and p-Me2NC6H4 and X = OPr(i) or NMe2, reveal that ring-opening of the morpholine-2,5-diones does occur, but that polymerization is terminated by the

  （3S，6S）-3-异丙基-6-甲基吗啉-2,5-二酮（1）和（3S，6S）-3,6-二甲基吗啉-2,5-二酮（2）如果不与丙交酯常用的金属催化剂前体以及辛酸锡（II）进行开环聚合反应，则只能得到低分子量的低聚物。与R2SnX2化合物的反应（其中R = Ph，Bu（n）和p-Me2NC6H4和X = OPr（i）或NMe2）显示确实发生了吗啉-2,5-二酮的开环，但聚合反应终止了通过形成动力学惰性的产物，例如Ph2Sn [mu，eta（3）-OCH（Me）CONCH（Pr（i））COOPr（i）]} 2（3）和[Bu（n）） 2Sn [mu，eta（3）-OCH（Me）CONCH（Me）CONMe2]} 2（4），除去HX。Ph3SnOPr（i）与吗啉2可逆反应，通过1 H NMR光谱分析甲苯-d8中的5-二酮，同时（Bu（n））3SnNMe2通过开环反应得到（Bu（n））3SnOCH