2-nitrosobenzene-1,4-diol | 215431-75-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 2-nitrosobenzene-1,4-diol
• 英文别名: Chinon Hydroxylamin
• CAS: 215431-75-7
• 化学式: C₆H₅NO₃
• 分子量: 139.111
• InChiKey: ZLDDBABJEDGDOE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  69.9
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  对苯二酚 在 盐酸 作用下， 以 水 为溶剂， 反应 0.7h， 以35%的产率得到2-nitrosobenzene-1,4-diol
  参考文献：
  名称：

  新型亚硝酸盐离子液体 (IL-ONO) 和固定在二氧化硅上的有机硅烷基亚硝酸盐离子液体纳米颗粒作为用于亲电芳香亚硝化的亚硝源

  摘要：

  摘要 利用新型亚硝酸离子液体 (IL-ONO) 和固定化亚硝酸离子液体开发了一种合成亚硝基芳烃的改进方法。这些离子液体在 0–5 °C 下作为活性芳烃的亲电芳族亚硝化的亚硝基源。它们的作用是在水中完成的，在温和的条件下，在很短的反应时间内获得了令人满意的结果。

  DOI：

  10.1016/j.crci.2011.09.012

文献信息

• IMMUNE REGULATORY OLIGONUCLEOTIDE (IRO) COMPOUNDS TO MODULATE TOLL-LIKE RECEPTOR BASED IMMUNE RESPONSE
  申请人：Idera Pharmaceuticals, Inc.

  公开号：EP2982679A1

  公开（公告）日：2016-02-10

  The invention provides novel immune regulatory oligonucleotides (IRO) as antagonist of TLRs and methods of use thereof. These IROs have unique sequences that inhibit or suppress TLR-mediated signaling in response to a TLR ligand or TLR agonist. The methods may have use in the prevention and treatment of cancer, an autoimmune disorder, airway inflammation, inflammatory disorders, infectious disease, skin disorders, allergy, asthma or a disease caused by a pathogen.

  本发明提供了作为 TLRs 拮抗剂的新型免疫调节寡核苷酸（IRO）及其使用方法。这些IRO具有独特的序列，可抑制或抑制TLR介导的对TLR配体或TLR激动剂的信号传导。这些方法可用于预防和治疗癌症、自身免疫性疾病、气道炎症、炎症性疾病、传染性疾病、皮肤病、过敏、哮喘或由病原体引起的疾病。
• REPTILE SKIN PRODUCT AND PRODUCTION METHOD FOR REPTILE SKIN PRODUCT
  申请人：Citizen Watch Co., Ltd.

  公开号：EP3653735A1

  公开（公告）日：2020-05-20

  A reptile leather article is formed by laminating an intermediate layer containing polyester polyurethane and a surface layer containing nitrocellulose, in that order, on the grain side of reptile leather. The reptile leather article preferably contains a hexavalent chromium reducing compound component capable of reducing hexavalent chromium into trivalent chromium. The hexavalent chromium reducing compound component is preferably at least one type selected from a compound (A-i) represented by formula (A-i) and a tannin (A-ii): (n represents 0, 1, or 2, R11 to R18 each independently represent a hydrogen atom, a hydroxy group, or the like, at least one of R11 to R14, R16, and R17 is a hydroxy group when n is 0, at least one of R11 to R18 is a hydroxy group when n is 1 or 2, and a plurality of R15 may be the same or different and a plurality of R18 may be the same or different when n is 2).

  将含有聚酯聚氨酯的中间层和含有硝化纤维素的表面层依次层压在爬行动物皮革的纹理面上，就形成了爬行动物皮革制品。爬行动物皮革制品最好含有一种六价铬还原化合物成分，能够将六价铬还原成三价铬。六价铬还原化合物成分最好是至少一种选自式 (A-i) 所代表的化合物 (A-i) 和单宁 (A-ii)： (n代表0、1或2，R11至R18各自独立地代表氢原子、羟基或类似物，当n为0时，R11至R14、R16和R17中至少有一个是羟基，当n为1或2时，R11至R18中至少有一个是羟基，当n为2时，多个R15可以相同或不同，多个R18可以相同或不同)。
• Non-toxic corrosion-protection pigments based on manganese
  申请人：——

  公开号：US20040011252A1

  公开（公告）日：2004-01-22

  Corrosion-inhibiting pigments based on manganese are described that contain a trivalent or tetravalent manganese/valence stabilizer complex. An inorganic or organic material is used to stabilize the trivalent or tetravalent manganese ion to form a compound that is sparingly soluble, exhibits low solubility, or is insoluble in water, depending upon the intended usage. Specific stabilizers are chosen to control the release rate of trivalent or tetravalent manganese during exposure to water and to tailor the compatibility of the powder when used as a pigment in a chosen binder system. Stabilizers may also modify the processing and handling characteristics of the formed powders. Manganese/valence stabilizer combinations are chosen based on the well-founded principles of manganese coordination chemistry. Many manganese-valence stabilizer combinations are presented that can equal the performance of conventional hexavalent chromium or tetravalent lead systems. It is emphasized that this abstract is provided to comply with the rules requiring an abstract which will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims.

  以锰为基础的缓蚀颜料含有三价或四价锰/价稳定剂复合物。一种无机或有机材料可用于稳定三价或四价锰离子，从而形成一种可少量溶解、溶解度低或不溶于水的化合物，具体取决于预期用途。选择特定的稳定剂是为了控制三价锰或四价锰在遇水时的释放率，并调整粉末在所选粘合剂体系中用作颜料时的相容性。稳定剂还可以改变成型粉末的加工和处理特性。锰/价稳定剂组合的选择是基于锰配位化学的基本原理。文中介绍了许多锰价稳定剂组合，其性能与传统的六价铬或四价铅体系相当。需要强调的是，提供本摘要是为了符合要求提供摘要的规则，以便检索者或其他读者快速确定技术公开的主题。提交本摘要的前提是，本摘要不用于解释或限制权利要求的范围或含义。
• Non-toxic corrosion-protection pigments based on rare earth elements
  申请人：——

  公开号：US20040104377A1

  公开（公告）日：2004-06-03

  A corrosion-inhibiting pigment comprising a rare earth element and a valence stabilizer combinded to form a rare earth/valence stabilizer complex. The rare earth element is selected from cerium, terbium, praseodymium, or a combination thereof, and at least one rare earth element is in the tetravalent oxidation state. An inorganic or organic material is used to stabilize the tetravalent rare earth ion to form a compound that is sparingly soluble in water. Specific stabilizers are chosen to control the release rate of tetravalent cerium, terbium, or praseodymium during exposure to water and to tailor the compatibility of the powder when used as a pigment in a chosen binder system. Stabilizers may also modify the processing and handling characteristics of the formed powders. Many rare earth-valence stabilizer combinations are presented that can equal the performance of conventional hexavalent chromium systems.

  一种缓蚀颜料，由稀土元素和价态稳定剂结合形成稀土/价态稳定剂复合物。稀土元素选自铈、铽、镨或它们的组合，至少有一种稀土元素处于四价氧化态。使用无机或有机材料来稳定四价稀土离子，以形成稀溶于水的化合物。选择特定的稳定剂是为了控制四价铈、铽或镨在遇水时的释放率，并调整粉末在所选粘合剂体系中用作颜料时的相容性。稳定剂还可以改变成型粉末的加工和处理特性。本文介绍了许多稀土-价稳定剂组合，其性能可与传统的六价铬体系媲美。
• [Bmim]NO2/H3BO3 as an effective nitrosonium source for electrophilic aromatic nitrosation under MW-promoted solvent-free conditions
  作者：Hassan Valizadeh、Hamid Gholipour

  DOI：10.1016/j.crci.2011.03.007

  日期：2011.10

  [Bmim]NO2/H3BO3 was used as a nitrosonium source for the efficient synthesis of nitrosoarenes. The reaction was accomplished under MW irradiation at 60W in a solventless system. Side processes such as oxidation or dealkylation were not observed during the nitrosation of alkyl phenyl ethers in the presence of this new reagent. The satisfactory results were obtained with very short reaction time, simplicity in the experimental procedure and good to excellent yields. (C) 2011 Academie des sciences. Published by Elsevier Masson SAS. All rights reserved.