1,6-bis(hydroxymethyl)naphthalene | 42050-10-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 1,6-bis(hydroxymethyl)naphthalene
• 英文别名: 1,6-Bishydroxymethylnaphthalin；[5-(Hydroxymethyl)naphthalen-2-yl]methanol
• CAS: 42050-10-2
• 化学式: C₁₂H₁₂O₂
• 分子量: 188.226
• InChiKey: MRLYBLJQUZGQKE-UHFFFAOYSA-N

物化性质

• 沸点：
  411.1±25.0 °C(Predicted)
• 密度：
  1.244±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1,6-bis(hydroxymethyl)naphthalene 在 盐酸 作用下， 反应 16.0h， 生成 1,6-bis(chloromethyl)naphthalene
  参考文献：
  名称：

  一种特别简单的双自由基制备方法。2. 1,3-、1,6-、2,6-和2,7-萘醌二甲烷的低温荧光光谱和常温激光诱导荧光光谱

  摘要：

  1,3-、1,6-、2,6- 和 2,7-萘并醌二甲烷是通过双（氯甲基）萘在 77 K 的玻璃介质中或在环境温度下的溶液中通过 KrF 光解 (254 nm) 获得的(249 nm) 激光闪光光解。这些物种通过荧光光谱检测和表征。

  DOI：

  10.1021/ja00002a033
• 作为产物：
  描述：

  1,6-双(溴甲基)萘 在 silver nitrate 作用下， 以 1,4-二氧六环 、 水 为溶剂， 反应 2.0h， 生成 1,6-bis(hydroxymethyl)naphthalene
  参考文献：
  名称：

  一种特别简单的双自由基制备方法。2. 1,3-、1,6-、2,6-和2,7-萘醌二甲烷的低温荧光光谱和常温激光诱导荧光光谱

  摘要：

  1,3-、1,6-、2,6- 和 2,7-萘并醌二甲烷是通过双（氯甲基）萘在 77 K 的玻璃介质中或在环境温度下的溶液中通过 KrF 光解 (254 nm) 获得的(249 nm) 激光闪光光解。这些物种通过荧光光谱检测和表征。

  DOI：

  10.1021/ja00002a033

文献信息

• Naphthylenyl compounds for long-acting injectable compositions and related methods
  申请人：Alkermes Pharma Ireland Limited

  公开号：US10799496B2

  公开（公告）日：2020-10-13

  The present invention provides compounds useful for the treatment of opioid dependence, alcohol dependence, alcohol use disorder, or the prevention of relapse to opioid dependence in a subject in need thereof. Related pharmaceutical compositions and methods are also provided herein.

  本发明提供的化合物可用于治疗阿片类药物依赖、酒精依赖、酒精使用障碍，或防止有需要的受试者复发阿片类药物依赖。本文还提供了相关的药物组合物和方法。
• Fire retardant resin composition, method of its production, shaped articles comprising the same, and silica
  申请人：Sugioka Takuo

  公开号：US20060167164A1

  公开（公告）日：2006-07-27

  The present invention has for its object to provide a fire retardant resin composition which is not only halogen-free and, hence, eliminating the adverse effect to the environment and human physiology but also reflecting an excellent fire retardancy imparted to a polyphenol having inherently favorable physical properties and heat resistance. The present invention is a fire retardant resin composition comprising a polyphenol compound and an inorganic microfine particle, wherein said polyphenol compound has such a structure that aromatic units each having at least one phenolic hydroxyl group are connected to one another through an organic unit containing two or more carbon atoms, and said inorganic microfine particle is a product of hydrolysis and condensation of an alkoxide compound and/or a carboxylic acid salt compound.

  本发明的目的是提供一种阻燃树脂组合物，该组合物不仅不含卤素，因而消除了对环境和人体生理的不利影响，而且反映了具有固有良好物理性能和耐热性能的多酚所赋予的优异阻燃性。本发明是一种阻燃树脂组合物，包括一种多酚化合物和一种无机微细颗粒，其中所述多酚化合物具有这样一种结构，即每个具有至少一个酚羟基的芳香单元通过含有两个或两个以上碳原子的有机单元相互连接，而所述无机微细颗粒是烷氧基化合物和/或羧酸盐化合物水解和缩合的产物。
• [EN] FIRE RETARDANT RESIN COMPOSITION, METHOD OF ITS PRODUCTION, SHAPED ARTICLES COMPRISING THE SAME, AND SILICA<br/>[FR] COMPOSITION DE RESINE IGNIFUGE, SON PROCEDE DE FABRICATION, ARTICLES FORMES LA COMPRENANT ET SILICE
  申请人：NIPPON CATALYTIC CHEM IND

  公开号：WO2003099934A1

  公开（公告）日：2003-12-04

  The present invention has for its object to provide a fire retardant resin composition which is not only halogen-free and, hence, eliminating the adverse effect to the environment and human physiology but also reflecting an excellent fire retardancy imparted to a polyphenol having inherently favorable physical properties and heat resistance. The present invention is a fire retardant resin composition comprising a polyphenol compound and an inorganic microfine particle, wherein said polyphenol compound has such a structure that aromatic units each having at least one phenolic hydroxyl group are connected to one another through an organic unit containing two or more carbon atoms, and said inorganic microfine particle is a product of hydrolysis and condensation of an alkoxide compound and/or a carboxylic acid salt compound.

  本发明的目的是提供一种阻燃树脂组合物，该组合物不仅不含卤素，从而消除了对环境和人体生理的不良影响，而且还通过一种具有内在良好物理特性和耐热性的聚苯酚表现出优异的阻燃性。本发明是一种阻燃树脂组合物，包含聚苯酚化合物和无机超微细颗粒，其中所述聚苯酚化合物具有这样的结构，即每个具有至少一个苯酚羟基的芳香单元通过包含两个或更多碳原子的有机单元相互连接，所述无机超微细颗粒是由烷氧基化合物和/或羧酸盐化合物水解和缩聚得到的产品。
• FIRE RETARDANT RESIN COMPOSITION, METHOD OF ITS PRODUCTION, SHAPED ARTICLES COMPRISING THE SAME, AND SILICA
  申请人：Nippon Shokubai Co., Ltd.

  公开号：EP1507829A1

  公开（公告）日：2005-02-23
• PHOTORESIST UNDERCOAT-FORMING MATERIAL AND PATTERNING PROCESS
  申请人：Hatakeyama Jun

  公开号：US20100104977A1

  公开（公告）日：2010-04-29

  A material comprising a novolac resin having a C 6 -C 30 aromatic hydrocarbon group substituted with a sulfo group or an amine salt thereof is useful in forming a photoresist undercoat. The undercoat-forming material has an extinction coefficient sufficient to provide an antireflective effect at a thickness of at least 200 nm, and a high etching resistance as demonstrated by slow etching rates with CF 4 /CHF 3 gas for substrate processing.