1-(1,10-phenanthrolinyl)-2,5-di(2-thienyl)-1H-pyrrole | 1268467-10-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 菲咯啉
• 英文名称: 1-(1,10-phenanthrolinyl)-2,5-di(2-thienyl)-1H-pyrrole
• 英文别名: PhenTPy；5-[2,5-Di (thiophen-2-yl)-1h-pyrrol-1-yl]-1,10-phenanthroline；5-(2,5-dithiophen-2-ylpyrrol-1-yl)-1,10-phenanthroline
• CAS: 1268467-10-2
• 化学式: C₂₄H₁₅N₃S₂
• 分子量: 409.535
• InChiKey: MOQWONDNBYSDJP-UHFFFAOYSA-N

物化性质

• 熔点：
  130-131 °C
• 沸点：
  649.6±50.0 °C(predicted)
• 密度：
  1.37±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.6
• 重原子数：
  29
• 可旋转键数：
  3
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  87.2
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  1,4-双(2-噻吩基)-1,4-丁二酮 、 1,10-菲罗啉-5-氨基 在 对甲苯磺酸 作用下， 以 甲苯 为溶剂， 反应 32.0h， 以85%的产率得到1-(1,10-phenanthrolinyl)-2,5-di(2-thienyl)-1H-pyrrole
  参考文献：
  名称：

  Electrochemical Polymerization of Ruthenium(II) Complex and Application to Acetaminophen Analysis

  摘要：

  一种新型钌（II）络合物[$RuCl_2(DMSO)_2$(PhenTPy)]是通过在$CHCl_3$溶液中，将$RuCl_2(DMSO)_4$与（1-(1,10-菲咯啉基)-2,5-二(2-噻吩基)-1H-吡咯）[PhenTPy]缩合而合成的。[$RuCl_2(DMSO)_2$(PhenTPy)]络合物修饰电极是通过在0.1 M四丁基高氯酸铵（TBAP）/$CH_2Cl_2$溶液中，对单体进行电聚合法而制成的，以利用金属离子中心之间的电子通信。紫外-可见光谱（UV）、质谱（MS）和循环伏安法（CV）被用于表征[$RuCl_2(DMSO)_2$(PhenTPy)]络合物及其聚合物（聚-Ru（II）苯络合物）。聚-Ru（II）苯络合物修饰电极对对乙酰氨基酚的氧化表现出电催化活性，该催化性能可用于在磷酸盐缓冲溶液（pH

  DOI：

  10.5012/bkcs.2011.32.4.1341

文献信息

• Electrochemical Polymerization of Ruthenium(II) Complex and Application to Acetaminophen Analysis
  作者：Sethuraman Kannan、Jung-Ik Son、Jee-Eun Yang、Yoon-Bo Shim

  DOI：10.5012/bkcs.2011.32.4.1341

  日期：2011.4.20

  A novel ruthenium(II) complex, [$RuCl_2(DMSO)_2$(PhenTPy)] has been synthesized by the condensation of $RuCl_2(DMSO)_4$ with (1-(1,10-phenanthrolinyl)-2,5-di(2-thienyl)-1H-pyrrole)[PhenTPy] in $CHCl_3$ solution. The [$RuCl_2(DMSO)_2$(PhenTPy)] complex modified electrode was fabricated through the electropolymerization of the monomer in a 0.1 M tetrabutylammonium perchlorate (TBAP)/$CH_2Cl_2$ solution, to take advantage of the electronic communication between metal ion center by the conjugated backbone. The UV-visible spectroscopy (UV), mass spectrometry (MS), and cyclic voltammetry (CV) were employed to characterize the [$RuCl_2(DMSO)_2$(PhenTPy)] complex and its polymer (poly-Ru(II)Phen complex). The poly-Ru(II)Phen complex modified electrode exhibited an electrocatalytic activity to the oxidation of acetaminophen and the catalytic property was used for the analysis of acetaminophen at the concentration range between 0.09 and 0.01 mM in a phosphate buffer solution (pH 7.0).

  一种新型钌（II）络合物[$RuCl_2(DMSO)_2$(PhenTPy)]是通过在$CHCl_3$溶液中，将$RuCl_2(DMSO)_4$与（1-(1,10-菲咯啉基)-2,5-二(2-噻吩基)-1H-吡咯）[PhenTPy]缩合而合成的。[$RuCl_2(DMSO)_2$(PhenTPy)]络合物修饰电极是通过在0.1 M四丁基高氯酸铵（TBAP）/$CH_2Cl_2$溶液中，对单体进行电聚合法而制成的，以利用金属离子中心之间的电子通信。紫外-可见光谱（UV）、质谱（MS）和循环伏安法（CV）被用于表征[$RuCl_2(DMSO)_2$(PhenTPy)]络合物及其聚合物（聚-Ru（II）苯络合物）。聚-Ru（II）苯络合物修饰电极对对乙酰氨基酚的氧化表现出电催化活性，该催化性能可用于在磷酸盐缓冲溶液（pH
• ELECTRON TRANSFER MEDIATORS FOR ENZYME-BASED BIOSENSOR
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  公开号：US20140102896A1

  公开（公告）日：2014-04-17

  A new ferrous complex capable of being used as an electron transfer mediator for a glucose sensor, a biosensor, and the like, is provided, which measure a glucose concentration in blood, in which the new ferrous complex exchanges rapidly and smoothly an electron between an enzyme and electrode, is strongly absorbed into electrode, and is stable, so that the new ferrous complex allows excellent sensitivity of a glucose sensor to be maintained.

  提供了一种新的铁配合物，可用作葡萄糖传感器、生物传感器等的电子转移介体，用于测量血液中的葡萄糖浓度。新的铁配合物能够在酶和电极之间快速、平稳地交换电子，强烈吸附到电极上，并且稳定，因此新的铁配合物可以保持葡萄糖传感器的优异灵敏度。
• Electron mediator and electrochemical biosensor employing the same
  申请人：Samsung Electronics Co., Ltd.

  公开号：US10094799B2

  公开（公告）日：2018-10-09

  Provided is an electron mediator system, which may include a first transition metal complex and a second transition metal complex, wherein a working potential of the electron mediator system may be substantially the same as a molar average of a working potential of the first transition metal complex and a working potential of the second transition metal complex.

  本文提供了一种电子介质系统，它可以包括第一过渡金属络合物和第二过渡金属络合物，其中电子介质系统的工作电位可以与第一过渡金属络合物的工作电位和第二过渡金属络合物的工作电位的摩尔平均值基本相同。
• Electron Mediator and Electrochemical Biosensor Employing the Same
  申请人：Samsung Electronics Co., Ltd.

  公开号：US20160054254A1

  公开（公告）日：2016-02-25

  Provided is an electron mediator system, which may include a first transition metal complex and a second transition metal complex, wherein a working potential of the electron mediator system may be substantially the same as a molar average of a working potential of the first transition metal complex and a working potential of the second transition metal complex.
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  申请人：——

  公开号：US9175328B2

  公开（公告）日：2015-11-03