4-(Ammoniomethyl)pyridinium dichloride

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 4-(Ammoniomethyl)pyridinium dichloride
• 英文别名: pyridin-1-ium-4-ylmethylazanium;dichloride
• 化学式: C6H10Cl2N2
• 分子量: 181.06
• InChiKey: VZTITPMLZPPLRB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.38
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  38.9
• 氢给体数：
  3
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  4-(1-acetyl-4(1H)-pyridylidene)-2-methyl-2-oxazolin-5-one 、 盐酸 以100%的产率得到
  参考文献：
  名称：

  HIROTA, KAZUHIRO;SHIMAMURA, MICHIYA;IKEDA, MIKIKO;OHMORI, SHINJI, J. HETEROCYCL. CHEM., 1982, 19, N 6, 1551-1552

  摘要：

  DOI：

文献信息

• DUAL INHIBITOR COMPOUNDS FOR USE IN THE TREATMENT OF NEURODEGENERATIVE DISORDERS AND ALZHEIMER'S DISEASE
  申请人：Fondazione Istituto Italiano di Tecnologia

  公开号：EP3154953A1

  公开（公告）日：2017-04-19
• Dual Inhibitor Compounds for Use in the Treatment of Neurodegenerative Disorders and Alzheimer's Disease
  申请人：FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA

  公开号：US20170096406A1

  公开（公告）日：2017-04-06

  The present invention relates to Compounds of Formula (I) and pharmaceutical compositions containing the same. It further relates to their use in the prevention or treatment of central nervous system diseases or disorders, in particular, cognitive, neurodegenerative or neuronal diseases or disorders.
• US9975861B2
  申请人：——

  公开号：US9975861B2

  公开（公告）日：2018-05-22
• [EN] DUAL INHIBITOR COMPOUNDS FOR USE IN THE TREATMENT OF NEURODEGENERATIVE DISORDERS AND ALZHEIMER'S DISEASE<br/>[FR] COMPOSÉS INHIBITEURS DOUBLES UTILISABLES DANS LE TRAITEMENT DE TROUBLES NEURODÉGÉNÉRATIFS ET DE LA MALADIE D'ALZHEIMER
  申请人：FOND ISTITUTO ITALIANO DI TECNOLOGIA

  公开号：WO2015189830A1

  公开（公告）日：2015-12-17

  The present invention relates to Compounds of Formula (I) and pharmaceutical compositions containing the same. It further relates to their use in the prevention or treatment of central nervous system diseases or disorders, in particular, cognitive, neurodegenerative or neuronal diseases or disorders.
• HIROTA, KAZUHIRO;SHIMAMURA, MICHIYA;IKEDA, MIKIKO;OHMORI, SHINJI, J. HETEROCYCL. CHEM., 1982, 19, N 6, 1551-1552
  作者：HIROTA, KAZUHIRO、SHIMAMURA, MICHIYA、IKEDA, MIKIKO、OHMORI, SHINJI

  DOI：——

  日期：——