3-Chloro-2-methyl-3-phenylpropanoic acid | 118508-83-1

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 苯丙酸
• 英文名称: 3-Chloro-2-methyl-3-phenylpropanoic acid
• CAS: 118508-83-1；118508-87-5
• 化学式: C₁₀H₁₁ClO₂
• 分子量: 198.649
• InChiKey: AHBFFEAZFAMESA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  1,1-双(三甲基甲硅烷氧基)-1-丙烯 、 苯甲醛 在 水 、 四氯化钛 作用下， 生成 3-Chloro-2-methyl-3-phenylpropanoic acid
  参考文献：
  名称：

  Mukaiyama反应的新进展：一锅合成β-氯酸和酯

  摘要：

  已经研究了乙烯酮甲硅烷基乙缩醛与苯甲醛的四氯化钛反应。通过醛醇氯化法，使用两当量的TiCl 4，可以良好的产率获得β-氯酸和酯。

  DOI：

  10.1016/s0040-4039(00)80275-0

文献信息

• PROCESS FOR THE PRODUCTION OF ETHYLENICALLY UNSATURATED ISOCYANATE BEARING ETHER LINKAGE
  申请人：Showa Denko K.K.

  公开号：EP2163540A1

  公开（公告）日：2010-03-17

  To provide a method for producing an ethylenically unsaturated group-containing isocyanate compound having an ether bond under such conditions that the ether bond is unlikely to be cleaved and the polymerization of an unsaturated group can be suppressed. The method for producing an ethylenically unsaturated group-containing isocyanate compound having an ether bond of the present invention is a method for producing an ethylenically unsaturated double bond-containing isocyanate compound from an amino alcohol having an ether bond and is characterized in that a reaction solvent in which the solubility of hydrogen chloride is 0.1 mole percent or less at 25°C is used.

  提供一种生产具有醚键的含乙烯不饱和基团的异氰酸酯化合物的方法，其生产条件是醚键不可能被裂解，并且可以抑制不饱和基团的聚合。本发明生产具有醚键的含乙烯基不饱和基团的异氰酸酯化合物的方法是一种从具有醚键的氨基醇生产含乙烯基不饱和双键的异氰酸酯化合物的方法，其特征在于使用的反应溶剂在 25℃时氯化氢的溶解度为 0.1 摩尔%或更低。
• METHOD FOR PRODUCING ETHYLENICALLY UNSATURATED GROUP-CONTAINING ISOCYANATE COMPOUND HAVING ETHER BOND
  申请人：Showa Denko K.K.

  公开号：EP2163540B1

  公开（公告）日：2014-01-08
• BELLASSOUED, MONCEF;DUBOIS, JACQUES-EMILE;BERTOUNESQUE, EMMANUEL, TETRAHEDRON LETT., 29,(1988) N 11, 1275-1278
  作者：BELLASSOUED, MONCEF、DUBOIS, JACQUES-EMILE、BERTOUNESQUE, EMMANUEL

  DOI：——

  日期：——
• ETHYLENICALLY UNSATURATED GROUP-CONTAINING ISOCYANATE COMPOUND AND PROCESS FOR PRODUCING THE SAME, AND REACTIVE MONOMER, REACTIVE (METH)ACRYLATE POLYMER AND ITS USE
  申请人：SHOWA DENKO K.K.

  公开号：EP1812381B1

  公开（公告）日：2011-02-16
• Ethylenically Unsaturated Group-Containing Isocyanate Compound and Process for Producing the Same, and Reactive Monomer, Reactive (Meth) Acrylate Polymer and its Use
  申请人：Nozawa Kaneo

  公开号：US20080132597A1

  公开（公告）日：2008-06-05

  There are provided a novel ethylenically unsaturated group-containing isocyanate compound, a process for producing the same, and a reactive monomer produced from the isocyanate compound, a reactive polymer and its use. The ethylenically unsaturated group-containing isocyanate compound according to the present invention is represented by formula (I).