(E)-1-(2-phenyl-2-p-methoxyphenylvinyl)-4-methoxybenzene | 15789-91-0

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: (E)-1-(2-phenyl-2-p-methoxyphenylvinyl)-4-methoxybenzene
• 英文别名: 4,4'-(1-phenylethene-1,2-diyl)bis(methoxybenzene)；trans-1,2-Di-p-anisyl-1-phenylethylen；trans-1,2-Dianisyl-1-phenylethen；Ethylene, 1,2-bis(p-methoxyphenyl)-1-phenyl-；1-methoxy-4-[(E)-2-(4-methoxyphenyl)-1-phenylethenyl]benzene
• CAS: 15789-91-0
• 化学式: C₂₂H₂₀O₂
• 分子量: 316.4
• InChiKey: CNEQSUVAQVEEPA-CJLVFECKSA-N

物化性质

• 熔点：
  105-107 °C
• 沸点：
  447.9±35.0 °C(Predicted)
• 密度：
  1.102±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  6
• 重原子数：
  24
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.09
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  cis-1,2-dianisyl-2-phenylvinyl bromide 在 lithium aluminium tetrahydride 、 iron(II) chloride 作用下， 以 四氢呋喃 为溶剂， 生成 (Z)-1-(2-phenyl-2-p-methoxyphenylvinyl)-4-methoxybenzene 、 (E)-1-(2-phenyl-2-p-methoxyphenylvinyl)-4-methoxybenzene
  参考文献：
  名称：

  Obafemi, Craig A.; Lee, Choi Chuck, Canadian Journal of Chemistry, 1990, vol. 68, # 11, p. 1998 - 2000

  摘要：

  DOI：

文献信息

• Palladium-catalyzed desulfitative hydroarylation of alkynes with sodium sulfinates
  作者：Saiwen Liu、Yang Bai、Xiangxiang Cao、Fuhong Xiao、Guo-Jun Deng

  DOI：10.1039/c3cc43723j

  日期：——

  A palladium-catalyzed desulfitative hydroarylation of alkynes with aryl sulfinic acid sodium salts is described. The reaction showed good regio- and stereoselectivity, and afforded the hydroarylation products in good yields. Various functional groups were well tolerated under the optimized reaction conditions.

  描述了炔烃与芳基亚磺酸钠盐的钯催化的脱硫加氢芳基化。该反应显示出良好的区域选择性和立体选择性，并以高收率提供了氢化芳基化产物。在优化的反应条件下，各种官能团均具有良好的耐受性。
• Triarylalkenes from the site-selective reductive cross-coupling of benzophenones and aldehydes
  作者：Anna I. Arkhypchuk、Nicolas D'Imperio、Sascha Ott

  DOI：10.1039/c9cc02972a

  日期：——

  PhP(Li)TMS converts benzophenones to phosphaalkenes which upon activation under oxidizing, basic conditions react with aromatic aldehydes under the formation of triarylalkenes. The one-pot reaction omits transition metals, proceeds at room temperature and precludes the formation of any homo-coupling products. Systematic substrate variations reveal reactivity patterns that are useful for the identification

  PhP（Li）TMS将二苯甲酮转化为磷烯烃，在氧化条件下活化后，碱性条件下与芳族醛发生反应，形成三芳基烯烃。一锅法反应省去了过渡金属，在室温下进行并且排除了任何均相偶联产物的形成。系统性底物变化揭示了可用于识别酮/醛组合的反应性模式，可将其偶联，收率可达80％。
• Exploratory Studies on the Reaction Between Iodoarenes and Acetylenes: One-pot, Pd-[Bmim][BF4] Catalyzed Preparation of Trianisylethylene
  作者：José C. Barros、Andrea L. F. Souza、Joaquim F. M. da Silva、O. A. C. Antunes

  DOI：10.1007/s10562-011-0549-7

  日期：2011.4

  The reaction between iodoarenes and acetylenes mediated by palladium was studied, showing selectivity changes based on the nature of the substituent. A new, phosphine-, copper-, and amine-free methodology was developed, in which the synthesis of trianisylethylene from 4-iodoanisole and trimethylsilylacetylene was promoted presumably by an N-heterocyclic-carbene derived from an ionic liquid and a palladium salt, using ethanol as the hydrogen source.
• METHODS, COMPOSITIONS, AND APPARATUSES FOR FORMING MACROCYCLIC COMPOUNDS
  申请人：Johnson, Thomas E.

  公开号：EP1716153B1

  公开（公告）日：2013-10-09
• Methods, compositions, and apparatuses for forming macrocyclic compounds
  申请人：Johnson E. Thomas

  公开号：US20070217965A1

  公开（公告）日：2007-09-20

  This invention relates to methods, compositions, and apparatuses for producing macrocyclic compounds. First, one or more reactants are provided in a reaction medium, which are capable of forming the macrocyclic compound through a desired reaction pathway that includes at least cyclization, and which are further capable of forming undesired oligomers through a undesired reaction pathway that includes undesirable oligomerization. Oligomerization of such reactions in the reaction medium is modulated to reduce formation of undesired oligomers and/or to reduce separation of the undesired oligomers from the reaction medium, relative to a corresponding unmodulated oligomerization reaction, thereby maximizing yields of the macrocyclic compound. The macrocyclic compound so formed is then recovered from the reaction medium. Preferably, the macrocyclic compound spontaneously separates from the reaction medium via phase separation. More preferably, the macrocyclic compound spontaneous precipitates from the reaction medium and therefore can be easily recovered by simple filtration.