1-chloro-7-fluoronaphthalene | 59079-73-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 1-chloro-7-fluoronaphthalene
• 英文别名: 1-Chloro-7-fluoronaphthalin
• CAS: 59079-73-1
• 化学式: C₁₀H₆ClF
• 分子量: 180.609
• InChiKey: ZODHXFYLZCSKNY-UHFFFAOYSA-N

物化性质

• 沸点：
  264.4±13.0 °C(Predicted)
• 密度：
  1.292±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  7-fluoro-1-naphthylamine 生成 1-chloro-7-fluoronaphthalene
  参考文献：
  名称：

  Substituent effects in the naphthalene ring system by fluorine-19 NMR

  摘要：

  DOI：

  10.1021/ja00423a012

文献信息

• A Visible Light and Iron‐mediated Carbocationic Route to Polysubstituted 1‐Halonaphthalenes by Benzannulation using Allylbenzenes and Polyhalomethanes
  作者：Irwan Iskandar Roslan、Hongwei Zhang、Kian‐Hong Ng、Stephan Jaenicke、Gaik‐Khuan Chuah

  DOI：10.1002/adsc.202001249

  日期：2021.2.16

  A wide array of polysubstituted 1‐bromo and chloronaphthalenes are obtained from coupling of allylbenzenes and polyhalomethanes. The reaction is mediated by iron metal under visible light irradiation and proceeds via a Kharasch addition intermediate followed by intramolecular FeIII mediated Friedel‐Crafts alkylation, with the formation of two Csp2−Csp2 bonds in the process. This method gives easy access

  烯丙基苯与多卤代甲烷的偶联可得到各种各样的多取代的1-溴和氯萘。该反应在可见光辐射下由铁金属介导，并通过Kharasch加成中间体进行，然后进行分子内Fe III介导的Friedel-Crafts烷基化，在此过程中形成两个C sp 2 -C sp 2键。该方法可轻松获得具有C-5至C-8取代基的1-卤代萘，否则难以合成。
• NAPHTHOBISCHALCOGENADIAZOLE DERIVATIVE AND PRODUCTION METHOD THEREFOR
  申请人：OSAKA UNIVERSITY

  公开号：US20190337966A1

  公开（公告）日：2019-11-07

  In order to provide a naphthobischalcogenadiazole derivative that can be used as an intermediate for producing a naphthobischalcogenadiazole compound into which a fluorine atom has been introduced, the naphthobischalcogenadiazole derivative in accordance with an aspect of the present invention is represented by a formula (I): where each of A 1 and A 2 is independently an oxygen atom, a sulfur atom, a selenium atom, or a tellurium atom; and each of X 1 and X 2 is independently a hydrogen atom, a halogen atom, a boronic acid group, a boronic acid ester group, a boronic acid diaminonaphthalene amide group, an N-methyliminodiacetic acid boronate group, a trifluoroborate salt group, or a triolborate salt group.

  为了提供一种可用作生产引入氟原子的萘基双硫/硒/碲-二唑化合物的中间体的萘基双硫/硒/碲-二唑衍生物，本发明的一个方面提供的萘基双硫/硒/碲-二唑衍生物由式(I)表示：其中，A1和A2分别独立地为氧原子、硫原子、硒原子或碲原子；X1和X2分别独立地为氢原子、卤素原子、硼酸基、硼酸酯基、硼酸二氨基萘酰胺基、N-甲基亚乙二酸硼酸酯基、三氟硼酸盐基或三羟基硼酸盐基。
• Naphthobischalcogenadiazole derivative and production method therefor
  申请人：OSAKA UNIVERSITY

  公开号：US10793584B2

  公开（公告）日：2020-10-06

  In order to provide a naphthobischalcogenadiazole derivative that can be used as an intermediate for producing a naphthobischalcogenadiazole compound into which a fluorine atom has been introduced, the naphthobischalcogenadiazole derivative in accordance with an aspect of the present invention is represented by a formula (I): where each of A1 and A2 is independently an oxygen atom, a sulfur atom, a selenium atom, or a tellurium atom; and each of X1 and X2 is independently a hydrogen atom, a halogen atom, a boronic acid group, a boronic acid ester group, a boronic acid diaminonaphthalene amide group, an N-methyliminodiacetic acid boronate group, a trifluoroborate salt group, or a triolborate salt group.

  为了提供一种萘二异噻二唑衍生物，该衍生物可用作生产引入了氟原子的萘二 异噻二唑化合物的中间体，根据本发明的一个方面，萘二异噻二唑衍生物由式 (I) 表示： 其中，A1 和 A2 各自独立地为氧原子、硫原子、硒原子或碲原子；X1 和 X2 各自独立地为氢原子、卤素原子、硼酸基团、硼酸酯基团、硼酸二氨基萘酰胺基团、N-甲基二乙酸硼酸盐基团、三氟硼酸盐基团或三硼酸盐基团。