US9205085, Msx-171 | 1352050-49-7

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: US9205085, Msx-171
• 英文别名: N-[[4-(anilinomethyl)cyclohexyl]methyl]aniline
• CAS: 1352050-49-7
• 化学式: C₂₀H₂₆N₂
• 分子量: 294.44
• InChiKey: LXYWJEHXFWSNFS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  22
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  24.1
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  1,4-环己烷二甲醇 、 苯胺 在 Pt-Sn/γ-Al2O3 作用下， 以 邻二甲苯 为溶剂， 反应 24.0h， 以93%的产率得到US9205085, Msx-171
  参考文献：
  名称：

  Heterogeneous bimetallic Pt–Sn/γ-Al2O3 catalyzed direct synthesis of diamines from N-alkylation of amines with diols through a borrowing hydrogen strategy

  摘要：

  Direct synthesis of diamines has been efficiently realized from the N-alkylation of amines with diols by means of heterogeneous bimetallic Pt-Sn/gamma-Al2O3 catalyst (0.5 wt % Pt, molar ratio Pt:Sn = 1:3) through a 'Borrowing Hydrogen' strategy under ligand-free conditions. The present methodology provides an environmentally benign route to diamines. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2011.10.100

文献信息

• Heterogeneous bimetallic Pt–Sn/γ-Al2O3 catalyzed direct synthesis of diamines from N-alkylation of amines with diols through a borrowing hydrogen strategy
  作者：Liandi Wang、Wei He、Kaikai Wu、Songbo He、Chenglin Sun、Zhengkun Yu

  DOI：10.1016/j.tetlet.2011.10.100

  日期：2011.12

  Direct synthesis of diamines has been efficiently realized from the N-alkylation of amines with diols by means of heterogeneous bimetallic Pt-Sn/gamma-Al2O3 catalyst (0.5 wt % Pt, molar ratio Pt:Sn = 1:3) through a 'Borrowing Hydrogen' strategy under ligand-free conditions. The present methodology provides an environmentally benign route to diamines. (C) 2011 Elsevier Ltd. All rights reserved.