Agn-PC-00jfbh | 920323-32-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: Agn-PC-00jfbh
• 英文别名: 4-[2-(dimethylamino)-1-(4-hydroxyphenyl)ethyl]-1-methylpiperidin-4-ol
• CAS: 920323-32-6
• 化学式: C₁₆H₂₆N₂O₂
• 分子量: 278.39
• InChiKey: FHCBKBSMAQMHET-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  20
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  46.9
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• Serotonin and norepinephrine reuptake inhibitors and uses thereof
  申请人：Shah M. Syed

  公开号：US20070015791A1

  公开（公告）日：2007-01-18

  Selective dual serotonin and norepinephrine reuptake inhibitors are provided. These compounds have a lower side-effect profile and are useful in compositions and products for use in treatment of a variety of conditions including depression, fibromyalgia, anxiety, panic disorder, agorophobia, post traumatic stress disorder, premenstrual dysphoric disorder, attention deficit disorder, obsessive compulsive disorder, social anxiety disorder, generalized anxiety disorder, autism, schizophrenia, obesity, anorexia nervosa, bulimia nervosa, Gilles de la Tourette Syndrome, vasomotor flushing, cocaine and alcohol addiction, sexual dysfunction, borderline personality disorder, fibromyalgia syndrome, diabetic neuropathic pain, chronic fatigue syndrome, pain, Shy Drager syndrome, Raynaud's syndrome, Parkinson's Disease, and epilepsy.
• US7687520B2
  申请人：——

  公开号：US7687520B2

  公开（公告）日：2010-03-30