N,N'-Dimethylguanidine hydrobromide | 13314-44-8

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N,N'-Dimethylguanidine hydrobromide
• 英文别名: N,N'dimethylguanidinium hydrobromide；N,N'-diaminoguanidine hydrobromide；N,N'-dimethyl-guanidine; hydrobromide；N,N'-Dimethyl-guanidin; Hydrobromid；N,N'-Dimethyl-guanidinium-bromid；1,3-DimMethylguanidinium；(Z)-[amino(methylamino)methylidene]-methylazanium;bromide
• CAS: 13314-44-8
• 化学式: BrH*C₃H₉N₃
• 分子量: 168.036
• InChiKey: CVAHOSSNEIXARZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -5.77
• 重原子数：
  7
• 可旋转键数：
  1
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  52
• 氢给体数：
  3
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  N,N'-Dimethylguanidine hydrobromide 生成 N-Chlor-N',N''-dimethyl-guanidin
  参考文献：
  名称：

  Heesing,A.; Schulze,H., Zeitschrift fur Naturforschung. Teil B. Anorganische Chemie, organische Chemie, Biochemie, Biophysik, Biologie, 1965, vol. 20, p. 536 - 539

  摘要：

  DOI：

文献信息

• Oxazolone derivatives and their use as anti-helicobacter pylori agents
  申请人：Takeda Chemical Industries, Ltd.

  公开号：US06414003B1

  公开（公告）日：2002-07-02

  An anti-Helicobacter pylori agent comprising a compound represented by the formula: wherein A represents an aromatic ring group which may be substituted; R1 and R2, whether identical or not, each represent a hydrogen atom or a hydrocarbon group which may be substituted; R3 and R4, whether identical or not, each represent a hydrogen atom, a hydrocarbon group which may be substituted, an acyl group, a carbamoyl group which may be substituted, or a carboxyl group which may be esterified; or a salt thereof.

  一种抗幽门螺杆菌剂，包括由以下公式表示的化合物：其中A代表可能被取代的芳香环基团；R1和R2，无论相同与否，每个代表氢原子或可能被取代的碳氢基团；R3和R4，无论相同与否，每个代表氢原子、可能被取代的碳氢基团、酰基、可能被取代的氨基甲酰基或可酯化的羧基；或其盐。
• Gmelin Handbuch der Anorganischen Chemie, Gmelin Handbook: Ni: MVol.C2, 8.9, page 901 - 911
  作者：

  DOI：——

  日期：——
• Synthesis of modified oligonucleotides containing 4-guanidino-2-pyrimidinone nucleobases
  作者：Jordi Robles、Anna Grandas、Enrique Pedroso

  DOI：10.1016/s0040-4020(00)00991-1

  日期：2001.1

  Oligionucleotides incorporating 4-guanidino-2-pyrimidinone nucleobases have been prepared. These nucleobase analogues were designed to mimic the double hydrogen bond donor pattern of protonated cytosines in parallel triple helices. Guanidine-, N-methyl-, N,N-dimethyl-, and N,N'-dimethylguanidine-containing nucleoside H-phosphonates were used for the synthesis of oligonucleotide analogues with minor modifications in standard solid-phase procedures. (C) 2000 Elsevier Science Ltd. All rights reserved.
• Preparation and properties of some acyl-guanidines
  作者：Ken Matsumoto、Henry Rapoport

  DOI：10.1021/jo01266a017

  日期：1968.2
• Chemistry and revised structure of suvanine
  作者：Lawrence V. Manes、Phillip Crews、Michael R. Kernan、D. John Faulkner、Frank R. Fronczek、Richard D. Gandour

  DOI：10.1021/jo00238a017

  日期：1988.2