(E,E)-3,4-diphenyl-2,4-hexadiene | 24815-65-4

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: (E,E)-3,4-diphenyl-2,4-hexadiene
• 英文别名: 3,4-diphenyl-2,4-hexadiene；3,4-diphenyl-hexa-2t,4t-diene；3,4-Diphenyl-hexa-2t,4t-dien；3.4-Diphenyl-trans-trans-hexadien-(2.4)；trans,trans-3,4-Diphenyl-hexa-2,4-dien；3,4-Diphenyl-hexadien-(2,4)；trans,trans-3,4-Diphenylhexa-2,4-diene；[(2E,4E)-4-phenylhexa-2,4-dien-3-yl]benzene
• CAS: 24815-65-4
• 化学式: C₁₈H₁₈
• 分子量: 234.341
• InChiKey: VTUNKULRSRAFHV-SCGPFSFSSA-N

物化性质

• 熔点：
  100-101 °C
• 沸点：
  316.6±12.0 °C(Predicted)
• 密度：
  0.980±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  6.1
• 重原子数：
  18
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  (E,E)-3,4-diphenyl-2,4-hexadiene 在 palladium on activated charcoal 作用下， 生成 1,4,5-trimethyl-2,3-diphenylbenzene
  参考文献：
  名称：

  �ber die Synthese von substituierten Terphenylen

  摘要：

  DOI：

  10.1007/bf00900103
• 作为产物：
  描述：

  cis-2,5-dimethyl-3,4-diphenyl-2,5-dihydrothiophene 在 间氯过氧苯甲酸 作用下， 以 氯仿 为溶剂， 生成 (E,E)-3,4-diphenyl-2,4-hexadiene
  参考文献：
  名称：

  从 α,α'-二酮硫化物高效制备多取代 1,3-二烯

  摘要：

  从容易获得的 α,α'-二酮硫化物开始，通过三个步骤以良好的总产率制备了一系列多取代的 1,3-二烯。

  DOI：

  10.1246/cl.1985.1173

文献信息

• A novel palladium(<scp>II</scp>) chloride-promoted addition–rearrangement reaction of terminal olefins with diphenylacetylene
  作者：Paul Mushak、Merle A. Battiste

  DOI：10.1039/c29690001146

  日期：——

  In the presence of palladium(II) chloride, ethylene and certain terminal olefins react with diphenylacetylene to give substituted alka-1,3-dienes derived from the symmetrical addition of two olefin units to the acetylenic reactant.

  在氯化钯（II）的存在下，乙烯和某些末端烯烃与二苯基乙炔反应，得到取代的烷基-1,3-二烯，该烷基衍生自将两个烯烃单元对称地加成到炔属反应物中。
• Using Alternative Therapies to Manage Chronic Illness Among Older Adults: An Examination of the Health Context, Predisposing and Enabling Processes
  作者：Andrew V. Wister、Minda Chittenden、Bonnie McCoy、Kelly Wilson、Trasey Allen、Melanie Wong

  DOI：10.1017/s0714980800000635

  日期：——

  This paper examines use of alternative therapies to manage a chronic illness among older adults with at least one of three major conditions: arthritis, heart disease, and hypertension. Drawing from developments in the health utilization literature, a focus is placed on the illness context, predisposing factors, and several factors deemed to enable persons to use complementary medicine. The baseline data (n = 879) from the 1995–96 North Shore Self-Care Study conducted in Vancouver, Canada were used for this study. Two dependent variables were analysed using logistic regression techniques – the first is based on a comprehensive question about using alternative therapies (such as herbal remedies, acupuncture, massage therapy, etc.) to manage a chronic condition; and the second uses a more specific question pertaining to meditation or praying. The results from the first analysis show that being younger, suffering from arthritis compared to hypertension, comorbidity, taking fewer medications, lower income, reading on the chronic condition, and the interaction between reading and illness self-efficacy are associated with trying alternative therapies. The findings for the second analysis show that being female, being younger, and not married, as well as reporting a more serious condition, illness duration and the interaction between having moderate levels of mutual aid and number of confidants result in a greater likelihood of trying meditation/prayer. Implications of these results are discussed in terms of their theoretical import, and their relevance for the degree to which unconventional and conventional medicine are complementary.

  摘要本文研究了患有关节炎、心脏病和高血压三种主要疾病中至少一种疾病的老年人使用替代疗法来控制慢性疾病的情况。本文借鉴了健康利用文献的发展，重点关注了疾病的背景、诱发因素以及被认为能够使人们使用补充医学的几个因素。本研究采用了 1995-96 年在加拿大温哥华进行的 "北岸自我保健研究 "的基线数据（n = 879）。使用逻辑回归技术对两个因变量进行了分析--第一个因变量是关于使用替代疗法（如草药、针灸、按摩疗法等）来控制慢性病的综合问题；第二个因变量是关于冥想或祈祷的更具体的问题。第一项分析的结果显示，年龄较小、患有关节炎而非高血压、合并症、服用较少的药物、收入较低、阅读有关慢性病的书籍以及阅读与疾病自我效能之间的相互作用与尝试替代疗法有关。第二项分析的结果表明，女性、年轻、未婚、病情较重、病程较长以及互助程度适中与知己人数之间的交互作用都会导致尝试冥想/祈祷的可能性增大。我们将从理论角度讨论这些结果的影响，以及它们对非常规医学和常规医学互补程度的意义。
• 219. The isomerisation of dienœstrol and some related dienes and indenes
  作者：Werner Hausmann、A. E. Wilder Smith

  DOI：10.1039/jr9490001030

  日期：——
• Dodds et al., Proceedings of the Royal Society of London. Series B, Biological sciences, 1953, vol. 140, p. 470,478
  作者：Dodds et al.

  DOI：——

  日期：——
• Chemistry of heavy carbene analogs R2M (M = Si, Ge, Sn). 8. Germylenes: singlets or triplets? [2 + 4]Cheletropic cycloadditions of dimethylgermylene and diiodogermylene to conjugated dienes
  作者：Michael Schriewer、Wilhelm P. Neumann

  DOI：10.1021/ja00342a043

  日期：1983.2