Cholylsarcosine | 93790-70-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: Cholylsarcosine
• 英文别名: 2-[methyl-[(4R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]acetic acid
• CAS: 93790-70-6
• 化学式: C₂₇H₄₅NO₆
• 分子量: 479.6
• InChiKey: DRRMEMPJCIGHMB-ZNLOGFMMSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  34
• 可旋转键数：
  6
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.93
• 拓扑面积：
  118
• 氢给体数：
  4
• 氢受体数：
  6

文献信息

• METHODS AND COMPOSITIONS FOR INHIBITING CLOSTRIDIUM DIFFICILE SPORE GERMINATION AND OUTGROWTH
  申请人：Sorg Joseph

  公开号：US20110280847A1

  公开（公告）日：2011-11-17

  Certain bile acids, including novel bile acids, and derivatives thereof can be used to inhibit the germination of C. difficile spores and/or the growth of C. difficile cells. The methods and compositions of the invention are useful for preventing and treating C. difficile -associated diseases, including but not limited to C. difficile colitis.
• Methods and Compositions for Inhibiting Clostridium difficile Spore Germination and Outgrowth
  申请人：Tufts University

  公开号：US20170056419A1

  公开（公告）日：2017-03-02

  Certain bile acids, including novel bile acids, and derivatives thereof can be used to inhibit the germination of C. difficile spores and/or the growth of C. difficile cells. The methods and compositions of the invention are useful for preventing and treating C. difficile -associated diseases, including but not limited to C. difficile colitis.
• US9340569B2
  申请人：——

  公开号：US9340569B2

  公开（公告）日：2016-05-17
• [EN] METHODS AND COMPOSITIONS FOR INHIBITING CLOSTRIDIUM DIFFICILE SPORE GERMINATION AND OUTGROWTH<br/>[FR] PROCÉDÉS ET COMPOSITIONS PERMETTANT D'EMPÊCHER LA GERMINATION ET L'EXCROISSANCE DES SPORES DE C. DIFFICILE
  申请人：UNIV TUFTS

  公开号：WO2010062369A2

  公开（公告）日：2010-06-03

  Certain bile acids, including novel bile acids, and derivatives thereof can be used to inhibit the germination of C. difficile spores and/or the growth of C. difficile cells. The methods and compositions of the invention are useful for preventing and treating C. difficile-associated diseases, including but not limited to C. difficile colitis.