Benzeneacetic acid, 4-(1-naphthalenylmethyl)- | 832730-94-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: Benzeneacetic acid, 4-(1-naphthalenylmethyl)-
• 英文别名: 2-[4-(naphthalen-1-ylmethyl)phenyl]acetic acid
• CAS: 832730-94-6
• 化学式: C₁₉H₁₆O₂
• 分子量: 276.3
• InChiKey: FAVBMXBFTXRCFF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5
• 重原子数：
  21
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• [EN] PHENYL ACETIC ACID DERIVATIVES AS HEPATOCYTE NUCLEAR FACTOR 4alpha (HNF-4alpha) MODULATOR COMPOUNDS<br/>[FR] DERIVES D'ACIDE PHENYL ACETIQUE UTILISES EN TANT QUE COMPOSES MODULATEURS DU FACTEUR NUCLEAIRE DES HEPATOCYTES 4 DOLLAR G(A) (FNH-4 DOLLAR G(A))
  申请人：LIGAND PHARMACUETICALS INC

  公开号：WO2005010202A2

  公开（公告）日：2005-02-03

  The present invention is directed to hepatocyte nuclear factor 4 α (HNF-4 α) receptor modulator compounds. This invention is also directed to pharmaceutical agents comprising such compounds as well as methods of using such compounds and pharmaceutical agents for modulating HNF-4 α receptors as well as processes mediated by HNF-4 α receptors. Also provided are methods of making such compounds and pharmaceutical agents, as well as intermediates used in their synthesis.