3-Methoxy-5-(1,1,5-trimethylhexyl)phenol | 296242-08-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 3-Methoxy-5-(1,1,5-trimethylhexyl)phenol
• 英文别名: 3-(2,6-dimethylheptan-2-yl)-5-methoxyphenol
• CAS: 296242-08-5
• 化学式: C₁₆H₂₆O₂
• 分子量: 250.38
• InChiKey: MCOVOQMVVFZSJF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.6
• 重原子数：
  18
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Topical formulations of resorcinols and cannibinoids and methods of use
  申请人：Immugen Pharmaceuticals, Inc.

  公开号：US20030232101A1

  公开（公告）日：2003-12-18

  In one aspect, the invention provides a method for preventing the transmission of HIV from one individual to another. In accordance with the method, a pharmacologically-acceptable composition including at least one resorcinol derivative compound and/or cannabinoid (e.g., cannabinol derivatives, &Dgr;8-THC derivatives, cannabichromene derivatives, cannabidiol derivatives, cannabigerol derivatives) (including combinations thereof) is administered topically to a first individual harboring HIV, or to a second individual at risk of infection with HIV, proximate in time with contact between the first individual and the second individual. The invention also provides topical formulations of at least one resorcinol and/or cannabinoid and water insoluble polymers as hydrogels.

  本发明提供了一种预防HIV从一个个体传播到另一个个体的方法。根据该方法，将至少包括一种间苯二酚衍生物化合物和/或大麻素（例如，大麻酚衍生物，Δ8-THC衍生物，大麻烯衍生物，大麻二酚衍生物，大麻醇衍生物）（包括其组合）的药理学可接受的组合物局部给第一具有HIV的个体，或在第一具有HIV的个体和第二个个体之间的接触时间接近时局部给第二个有HIV感染风险的个体。本发明还提供了至少包括一种间苯二酚和/或大麻素以及水不溶性聚合物作为水凝胶的局部制剂。
• Cannabinoid derivatives
  申请人：Travis Rick Craig

  公开号：US20070179135A1

  公开（公告）日：2007-08-02

  This invention discloses cannabinoid derivatives and pharmaceutical uses thereof.

  本发明揭示了大麻素衍生物及其药物用途。
• Resorcinolic compounds
  申请人：——

  公开号：US20020037923A1

  公开（公告）日：2002-03-28

  The invention provides a resorcinol derivative and a method of using the resorcinol derivative to attenuate the growth of a neoplasm.

  本发明提供了一种间苯二酚衍生物和一种使用间苯二酚衍生物抑制肿瘤生长的方法。
• Methods and compounds for inhibiting eicosanoid metabolism and platelet aggregation
  申请人：——

  公开号：US20020137802A1

  公开（公告）日：2002-09-26

  The invention provides a method for attenuating the aggregation and/or activation of blood platelets within a blood product. In accordance with this method, a cannabinoid or resorcinolic compound is introduced into the blood product under conditions sufficient to inhibit the aggregation and/or activation of blood platelets within the blood product. The invention also pertains to the use of a cannabinoid or resorcinolic compound to prepare a composition suitable for inhibiting the activation and/or aggregation of blood platelets and to such compositions. The invention also pertains to a method of selectively inhibiting COX-1 and thromboxane synthase within a cell or blood platelet.

  本发明提供了一种减弱血液制品中血小板聚集和/或活化的方法。根据该方法，在足以抑制血液制品中血小板聚集和/或活化的条件下，将大麻素或间苯二酚化合物引入血液制品中。本发明还涉及使用大麻素或间苯二酚化合物制备适用于抑制血小板活化和/或聚集的组合物以及此类组合物。本发明还涉及一种选择性抑制细胞或血小板内 COX-1 和血栓素合成酶的方法。
• Cannabinol derivatives
  申请人：——

  公开号：US20030158191A1

  公开（公告）日：2003-08-21

  The invention provides cannabinol derivatives and pharmaceutical preparations thereof.

  本发明提供大麻酚衍生物及其药物制剂。