雌三醇3-硫酸盐16-葡糖苷酸 | 4661-65-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 中文名称: 雌三醇3-硫酸盐16-葡糖苷酸
• 英文名称: Estriol 3-sulfate 16-glucuronide
• 英文别名: (2S,3S,4S,5R)-3,4,5-trihydroxy-6-[[(8R,9S,13S,14S,16R,17R)-17-hydroxy-13-methyl-3-sulfooxy-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-16-yl]oxy]oxane-2-carboxylic acid
• CAS: 4661-65-8
• 化学式: C₂₄H₃₂O₁₂S
• 分子量: 544.6
• InChiKey: ATNWFRGUDKUYOG-SUPAOECSSA-N

物化性质

• 密度：
  1.63±0.1 g/cm3(Predicted)
• 物理描述：
  Solid

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  37
• 可旋转键数：
  5
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  209
• 氢给体数：
  6
• 氢受体数：
  12

文献信息

• Total estriol fluorescence polarization immunoassay
  申请人：ABBOTT LABORATORIES

  公开号：EP0200960A1

  公开（公告）日：1986-11-12

  The present invention is directed to a homogeneous fluorescence polarization immunoassay for determining total estriol content in body fluids, to the various components needed for preparing and carrying out such an assay, and to methods of making these components. Specifically, tracers, immunogens and antibodies are disclosed, as well as methods for preparing them. The assay is conducted by measuring the degree of polarization of plane polarized light that has been passed through a sample containing antiserum and tracer. The combination of antiserum and tracer used will possess excellent cross-reactivity to estriol-3-sulfate, eliminating the need for enzyme hydrolysis of this conjugate to free estriol.

  本发明涉及一种测定体液中总雌三醇含量的均相荧光偏振免疫测定法，涉及制备和进行这种测定所需的各种成分，以及制备这些成分的方法。 具体地说，本发明公开了示踪剂、免疫原和抗体，以及制备它们的方法。 该测定法是通过测量穿过含有抗血清和示踪剂的样品的平面偏振光的偏振程度来进行的。 所使用的抗血清和示踪剂的组合将对雌三醇-3-硫酸盐具有极好的交叉反应性，从而无需用酶水解这种共轭物来生成游离雌三醇。
• Graphite electrode comprising electrochemically reduced graphene oxide and methods thereof
  申请人：KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS

  公开号：US10156539B2

  公开（公告）日：2018-12-18

  A modified graphite electrode comprising a coating of electrochemically reduced graphene oxide. The modified graphite electrode may be employed in detecting of uric acid. A sensing device comprising the modified graphite electrode and a method of making the modified graphite electrode are described herein.

  一种改性石墨电极，包括一层电化学还原氧化石墨烯涂层。改性石墨电极可用于检测尿酸。本文描述了一种包含改性石墨电极的传感装置和一种制造改性石墨电极的方法。
• Detection of serum methionine and glucose by graphite pencil electrode
  申请人：KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS

  公开号：US11474067B2

  公开（公告）日：2022-10-18

  A method of using a graphite electrode to measure a concentration of glucose or methionine from a biological sample is described. A mechanical pencil lead may be used, as the graphite electrode, and the biological sample may come from a patient's serum. The glucose or methionine may produce a peak current response within a range of 0.4-0.8 V when the sample is subjected to linear scan voltammetry.

  描述了一种使用石墨电极测量生物样本中葡萄糖或蛋氨酸浓度的方法。可以使用机械铅笔芯作为石墨电极，生物样本可以来自病人的血清。在对样品进行线性扫描伏安法测量时，葡萄糖或蛋氨酸可在 0.4-0.8 V 范围内产生峰值电流响应。
• JPS6061597A
  申请人：——

  公开号：JPS6061597A

  公开（公告）日：1985-04-09
• BIOSENSOR FOR CONTINUOUS MONITORING OF METABOLITES AND PROTEINS AND METHODS OF MANUFACTURE THEREOF
  申请人：Papadimitrakopoulos Fotios

  公开号：US20100116691A1

  公开（公告）日：2010-05-13

  A biosensor comprises a substrate; a reference electrode; a working electrode; a counter electrode; and a plurality of permeability adjusting spacers. The reference electrode, the working electrode and the plurality of permeability adjusting spacers are all being disposed to be substantially parallel to each other to create a plurality of enzyme containing porous sections. The enzyme containing porous sections contain an enzyme; where the enzyme is operative to react with a metabolite to determine the concentration of the metabolite. By combining a number of the aforementioned biosensors, the differential concentration of a target enzyme or protein is determined by monitoring the changes on its metabolite substrates.