Isoflupredone 21-phosphate | 432-44-0

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: Isoflupredone 21-phosphate
• 英文别名: [2-[(8S,9R,10S,11S,13S,14S,17R)-9-fluoro-11,17-dihydroxy-10,13-dimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] dihydrogen phosphate
• CAS: 432-44-0
• 化学式: C₂₁H₂₈FO₈P
• 分子量: 458.4
• InChiKey: UWJRRPBVAKDVFZ-BULBTXNYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.1
• 重原子数：
  31
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  141
• 氢给体数：
  4
• 氢受体数：
  9

文献信息

• MOTOR-ASSOCIATED NEURODEGENERATIVE DISEASE AND METHODS OF TREATMENT
  申请人：Verge Analytics, Inc.

  公开号：US20170360805A1

  公开（公告）日：2017-12-21

  Disclosed herein are methods and compounds for treating a motor-associated neurodegenerative disease or condition. In some instances, also included herein are methods and compounds for treating a TDP-43 associated neurodegenerative disease or condition (e.g., ALS and frontotemporal dementia) and/or a C9orf72 associated neurodegenerative disease or condition (e.g., ALS and frontotemporal dementia).
• [EN] MOTOR-ASSOCIATED NEURODEGENERATIVE DISEASE AND METHODS OF TREATMENT<br/>[FR] MALADIE NEURODÉGÉNÉRATIVE MOTRICE ET MÉTHODES DE TRAITEMENT
  申请人：VERGE ANALYTICS INC

  公开号：WO2017218815A1

  公开（公告）日：2017-12-21

  Disclosed herein are methods and compounds for treating a motor-associated neurodegenerative disease or condition. In some instances, also included herein are methods and compounds for treating a TDP-43 associated neurodegenerative disease or condition (e.g., ALS and frontotemporal dementia) and/or a C9orf72 associated neurodegenerative disease or condition (e.g., ALS and frontotemporal dementia).