3-丙氧基-3H-2-苯并呋喃-1-酮 | 99865-51-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并呋喃
• 中文名称: 3-丙氧基-3H-2-苯并呋喃-1-酮
• 英文名称: 3-propyloxyphthalide
• 英文别名: 3-propoxy-phthalide；3-Propoxy-phthalid；3-propoxyphthalide；1(3H)-Isobenzofuranone, 3-propoxy-；3-propoxy-3H-2-benzofuran-1-one
• CAS: 99865-51-7
• 化学式: C₁₁H₁₂O₃
• 分子量: 192.214
• InChiKey: DKKKJUOXSSKXPX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  丙醇 、 邻羧基苯甲醛 生成 3-丙氧基-3H-2-苯并呋喃-1-酮
  参考文献：
  名称：

  Reactions of Phthalaldehydic Acid

  摘要：

  DOI：

  10.1021/jo01356a022

文献信息

• Shim, Sang Chul; Lee, Dong Yub; Jiang, Li Hong, Journal of Heterocyclic Chemistry, 1995, vol. 32, # 1, p. 363 - 366
  作者：Shim, Sang Chul、Lee, Dong Yub、Jiang, Li Hong、Kim, Tae Jeong、Cho, Sung-Dong

  DOI：——

  日期：——
• JPH02184683A
  申请人：——

  公开号：JPH02184683A

  公开（公告）日：1990-07-19
• METHOD FOR TREATING OCULAR DEMODEX
  申请人：Gao Ying-Ying

  公开号：US20090214676A1

  公开（公告）日：2009-08-27

  The present invention relates to a method for treating a disorder chosen from ocular Demodex, Demodex -induced blepharitis, rosacea, acne, and meibomian gland dysfunction in a patient in need thereof, comprising administering to the patient a composition comprising a therapeutically effective amount of a substance chosen from at least one of an isoprenoidal essential oil such as Tea Tree Oil; Terpinen-4-ol; (+)-Carvone; alpha-Terpineol; Cardinene; d-Carvone; l-Carvone; gamma-Terpinene; alpha-Terpinene; 1,8-Cineole; alpha-Terpineol; para-Cimene; alpha-Pinene; Limonene; (R)-(+)-Limonene; alpha-Thugene; Eucalyptol; (+)-Ledene; Cuminic Aldehyde; and Myrcene; the administration comprising contacting or scrubbing an affected area of skin or hair, or eyelid margin and lashes of the patient with the composition; also disclosed are a method for treating mange and mite infestations on a mammalian animal; and kits for in-office and at home treatments of the disorders.
• Method for Treating Ocular Demodex
  申请人：Gao Ying-Ying

  公开号：US20120004320A1

  公开（公告）日：2012-01-05

  The present invention relates to a method for treating a disorder chosen from ocular Demodex, Demodex -induced blepharitis, rosacea, acne, and meibomian gland dysfunction in a patient in need thereof, comprising administering to the patient a composition comprising a therapeutically effective amount of a substance chosen from at least one of an isoprenoidal essential oil such as Tea Tree Oil; Terpinen-4-ol; Carvone; alpha-Terpineol; Cardinene; d-Carvone; l-Carvone; gamma-Terpinene; alpha-Terpinene; 1,8-Cineole; alpha-Terpineol; para-Cimene; alpha-Pinene; Limonene; (R)-(+)-Limonene; alpha-Thugene; Eucalyptol; (+)-Ledene; Cuminic Aldehyde; and Myrcene; the administration comprising contacting or scrubbing an affected area of skin or hair, or eyelid margin and lashes of the patient with the composition; also disclosed are a method for treating mange and mite infestations on a mammalian animal; and kits for in-office and at home treatments of the disorders.
• EYE TREATMENT
  申请人：Nichamin Louis D.

  公开号：US20130331768A1

  公开（公告）日：2013-12-12

  Methods and kits for treating or preventing an eye condition or for cleaning an eye area tissue are provided. A method of the invention includes administering an isoprenoidal essential oil to eye area tissue, chafing eye area tissue with an abrasive, and removing the abrasive. A kit according to the invention includes an isoprenoidal essential oil, an abrasive for chafing eye area tissue, and in instruction for use for treating an eye condition or cleansing an eye area tissue. The invention also includes a composition of matter comprising an isoprenoidal essential oil and a plurality of abrasive particles in ophthamologically acceptable base.