4-Butoxy-3-fluorophenol | 54509-31-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 4-Butoxy-3-fluorophenol
• 英文别名: 4-butoxy-3-fluorophenol
• CAS: 54509-31-8
• 化学式: C₁₀H₁₃FO₂
• 分子量: 184.21
• InChiKey: GDXAFAFPRVVQEE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• COMPOUNDS AND METHODS FOR TRANS-MEMBRANE DELIVERY OF MOLECULES
  申请人：Aposense Ltd.

  公开号：US20170037401A1

  公开（公告）日：2017-02-09

  A novel delivery system for drugs, and especially macromolecules such as proteins or oligonucleotides through biological membranes is provided, and specifically delivery of siRNA. The delivery system comprises conjugation of the macromolecule drug to a moiety that enables effective passage through the membranes. Respectively, novel compounds and pharmaceutical compositions are provided, utilizing said delivery system. In one aspect of the invention, the compounds may be utilized in medical practice, for example, in delivery of siRNA or antisense oligonucleotides across biological membranes for the treatment of medical disorders.