octadecyldimethylammonium bromide | 75633-74-8

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: octadecyldimethylammonium bromide
• 英文别名: DOAB；stearyl dimethyl ammonium bromide；dimethyl octadecyl ammonium bromide；N,N-dimethyloctadecan-1-amine;hydrobromide
• CAS: 75633-74-8
• 化学式: BrH*C₂₀H₄₃N
• 分子量: 378.48
• InChiKey: QMDUPVPMPVZZGK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.39
• 重原子数：
  22
• 可旋转键数：
  17
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  3.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  octadecyldimethylammonium bromide 、 4’,4'',4''',4''''-(ethene-1,1,2,2-tetrayl)tetrabiphenyl-4-carboxylic acid potassium salt 以 乙醇 、 水 为溶剂， 以97.5%的产率得到ETTC-DOAB
  参考文献：
  名称：

  基于四苯基乙烯离子络合物的二价铜离子荧 光探针及制备方法及用途

  摘要：

  本发明公开了基于四苯基乙烯离子络合物的二价铜离子荧光探针及制备方法及用途，该探针用式(V)所示：本发明的荧光探针化学稳定性好，具有较高的固体荧光量子产率。在检测体系Cu2+的含量中可以表现出较高的选择性、较高的灵敏度，并且可达到瞬时响应。在一定铜离子浓度范围内，荧光强度呈线性变化，计算得到的检测限为12.60nM。本发明中的荧光探针与传统的荧光探针制备方法相比，具有操作简单、产率高、易于提纯、绿色环保等优点，便于大规模生产应用。

  公开号：

  CN107188801B

文献信息

• Additives and products including oligoesters
  申请人：——

  公开号：US20030199593A1

  公开（公告）日：2003-10-23

  The present invention relates to oligoesters and their use or the creation of additives. Oligoester containing additives and/or oligoesters themselves may be used for formulating pharmaceutical preparations, cosmetics or personal care products such as shampoos and conditioners. These oligoesters are particularly useful for the creation of multi-purpose additives that can impart conditioning, long substantivity and/or UV protection. Individual oligoesters and oligoester mixtures are described.

  本发明涉及寡酯及其用途或添加剂的制备。含有寡酯的添加剂和/或寡酯本身可用于配制药物制剂、化妆品或个人护理产品，如洗发水和护发素。这些寡酯对于制备能够赋予调理、长效性和/或紫外线保护的多功能添加剂特别有用。描述了单独的寡酯和寡酯混合物。
• Imidazoline quats
  申请人：Croda, Inc.

  公开号：US20040220062A1

  公开（公告）日：2004-11-04

  Mixture of dialkyl imidazoline quats with specified substitution content are provided. In one embodiment, at least a portion of the mixture includes at least one dialkyl imidazoline quat having at least one C 16 -C 30 alkyl group; the C 16-30 substitution content of the mixture being from about 10% to about 95% with respect to C 10+ reference substitution range. Methods of making imidazoline quats and quat mixtures, personal care and cosmetic products and formulations that contain the imidazoline quats and quat mixtures, methods of making such personal care and cosmetic products and formulations, and methods of using the such imidazoline quats, quat mixtures, and personal care and cosmetic products and formulations are also provided. Various embodiments are disclosed.

  提供具有指定取代含量的二烷基咪唑啉季铵盐混合物。在一个实施例中，至少部分混合物包括至少一种具有至少一个C16-C30烷基基团的二烷基咪唑啉季铵盐；混合物的C16-C30取代含量相对于C10+参考取代范围约为10%至95%。还提供制备咪唑啉季铵盐和季铵盐混合物的方法，包含咪唑啉季铵盐和季铵盐混合物的个人护理和化妆品产品和配方，制备这种个人护理和化妆品产品和配方的方法，以及使用这种咪唑啉季铵盐、季铵盐混合物、个人护理和化妆品产品和配方的方法。还披露了各种实施例。
• FORMULATION AND DELIVERY OF MODIFIED NUCLEOSIDE, NUCLEOTIDE, AND NUCLEIC ACID COMPOSITIONS
  申请人：MODERNA THERAPEUTICS, INC.

  公开号：US20160038612A1

  公开（公告）日：2016-02-11

  The present disclosure provides, inter alia, formulation compositions comprising modified nucleic acid molecules which may encode a protein, a protein precursor, or a partially or fully processed form of the protein or a protein precursor. The formulation composition may further include a modified nucleic acid molecule and a delivery agent. The present invention further provides nucleic acids useful for encoding polypeptides capable of modulating a cell's function and/or activity.

  本公开提供了包含修饰核酸分子的配方组合，该核酸分子可以编码蛋白质、蛋白质前体或蛋白质或蛋白质前体的部分或完全加工形式的组合物。该配方组合还可以包括一种修饰核酸分子和一种传递剂。本发明还提供了用于编码能够调节细胞功能和/或活性的多肽的核酸。
• Compositions containing esters of aromatic alkoxylated alcohols and fatty carboxylic acids
  申请人：——

  公开号：US20030161792A1

  公开（公告）日：2003-08-28

  A personal care or cosmetic product composition that includes from about 0.1% to about 99% of at least one ester of alkoxylated aromatic alcohol and fatty carboxylic acid, and from about 0.1% to 60% of at least one functional ingredient is provided. The functional ingredients in the composition may include active ingredients and additional ingredients. Especially suitable active ingredients are sunscreen active ingredients and antiperspirant active ingredients. Preferred compositions are sunscreen product formulations and antiperspirant products. In one preferred embodiment, the composition further includes at least one cyclomethicone compound present in the amount of from about 1% to 99% by weight of the composition. A method of improving the protection of human or animal skin or hair from radiation and a method of improving the protection of human or animal skin or hair from perspiration are also provided.

  提供一种个人护理或化妆品组合物，包括约0.1%至约99%的至少一种烷氧基芳香醇和脂肪羧酸酯，以及约0.1%至60%的至少一种功能性成分。组合物中的功能性成分可能包括活性成分和额外成分。特别适用的活性成分包括防晒活性成分和止汗活性成分。首选的组合物是防晒产品配方和止汗产品。在一个首选实施例中，该组合物还包括至少一种环硅烷化合物，其占组合物重量的约1%至99%。还提供了一种改善人类或动物皮肤或毛发免受辐射的保护的方法，以及一种改善人类或动物皮肤或毛发免受汗水侵害的方法。
• Pharmaceutical preparation containing magnetic vesicular particles, manufacturing method thereof and diagnostic therapeutic system
  申请人：Takeyama Toshihisa

  公开号：US20060099145A1

  公开（公告）日：2006-05-11

  A pharmaceutical preparation containing magnetic vesicular particles is disclosed, wherein the magnetic vesicular particles each include magnetic microparticles within a lipid membrane, an organic compound having at least two groups selected from the group consisting of a hydroxyl group, a carboxyl group, a carbamoyl group, an amino group, a mercapto group, a sulfo group, a dithio group, a thiocarboxyl group and a dithiocarboxyl group is bonded to the magnetic microparticle, and the magnetic vesicular particles satisfy the following equation: 0.05≦ R /( r ×100)≦1.5 wherein R represents an average grain size of the magnetic vesicular particles and r represents an average particle size of magnetic microparticles included in the magnetic vesicular particles.

  本发明涉及一种含有磁性囊泡颗粒的制剂，其中磁性囊泡颗粒包括磁性微粒在脂质膜内，有机化合物与磁性微粒键合，该有机化合物至少具有羟基、羧基、氨基、硫醇基、磺酸基、二硫基、硫代羧酸基和二硫代羧酸基中的两种基团。磁性囊泡颗粒满足以下方程式：0.05≦R/(r×100)≦1.5，其中R表示磁性囊泡颗粒的平均粒径，r表示磁性微粒的平均粒径。