3-氯-3-乙基庚烷 | 28320-89-0

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 有机氯化物
• 中文名称: 3-氯-3-乙基庚烷
• 英文名称: 3-chloro-3-ethylheptane
• 英文别名: 3-Chlor-3-ethylheptan；3-ethyl-3-chloro-heptane；3-Aethyl-3-chlor-heptan
• CAS: 28320-89-0
• 化学式: C₉H₁₉Cl
• 分子量: 162.703
• InChiKey: KLRHBXRASJUOMM-UHFFFAOYSA-N

物化性质

• 沸点：
  46 °C(Press: 3 Torr)
• 密度：
  0.8856 g/cm3

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  10
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  3-氯-3-乙基庚烷 在 zinc-modified cyanoborohydride 作用下， 以 乙醚 为溶剂， 反应 2.5h， 以96%的产率得到3-乙基庚烷
  参考文献：
  名称：

  锌改性的氰基硼氢化物在乙醚中选择性还原叔卤，烯丙基卤和苄基卤

  摘要：

  在乙醚中的锌改性氰基硼氢化物将叔卤代，烯丙基卤和苄基卤还原为相应的烃，但该试剂对伯烷基卤，仲烷基卤，乙烯基卤和芳基卤呈惰性。

  DOI：

  10.1016/s0040-4039(00)86272-3
• 作为产物：
  描述：

  戊酸乙酯 在 盐酸 作用下， 生成 3-氯-3-乙基庚烷
  参考文献：
  名称：

  The Treatment of Facial Verrucae With the Pulsed Dye Laser

  摘要：

  AbstractObjectives/Hypothesis To evaluate the treatment of facial verrucae with the pulsed dye laser.Study Design A prospective, nonrandomized, nonblinded pilot study evaluating the treatment of facial verrucae with the pulsed dye laser.Methods Twelve patients with facial verrucae (four recalcitrant) were identified and followed in the study in the setting of a tertiary referral center. The treatment consisted of the flash‐lamp pumped pulsed dye laser (585 mn) with a spot size of 5 mm at fluences between 9.0 and 13 J/cm2. Each lesion received one or two pulses with 2 mm of surrounding normal skin included in the treatment. One patient had paring prior to pulse treatment. The patients were examined 3 to 4 weeks after each procedure, and clinical assessment of the lesion was documented.Results Patient ages ranged from 18 to 47 years. Four patients had refractory lesions, and eight patients had never undergone previous treatment. All 12 patients had full resolution of their facial warts after one to three treatment sessions. No complications such as scarring, alopecia, or recurrence were encountered. Follow‐up ranged from 10 to 33 months.Conclusions Pulsed dye laser therapy is highly effective and safe therapy for facial verrucae. This method appears to selectively destroy warts without damaging surrounding skin.

  DOI：

  10.1097/00005537-200209000-00007

文献信息

• Selective reduction of tertiary, allyl, and benzyl halides by zinc-modified cyanoborohydride in diethyl ether
  作者：Sunggak Kim、Yong Jin Kim、Kyo Han Ahn

  DOI：10.1016/s0040-4039(00)86272-3

  日期：1983.1

  Zinc-modified cyanoborohydride in diethyl ether reduces tertiary, allyl, and benzyl halides to the corresponding hydrocarbons but the reagent is inert toward primary alkyl, secondary alkyl, vinyl, and aryl halides.

  在乙醚中的锌改性氰基硼氢化物将叔卤代，烯丙基卤和苄基卤还原为相应的烃，但该试剂对伯烷基卤，仲烷基卤，乙烯基卤和芳基卤呈惰性。
• Kim, Sunggak; Hong, Chang Yong; Yang, Sungbong, Angewandte Chemie, 1983, vol. 95, # 7, p. 568 - 569
  作者：Kim, Sunggak、Hong, Chang Yong、Yang, Sungbong

  DOI：——

  日期：——
• Synthesis of ethylenes with acyclic quaternary carbons by dehydration of neopentyl alcohols. Application of the 2-D INAPT technique
  作者：C. A. Drake、Norman Rabjohn、Michael S. Tempesta、Richard B. Taylor

  DOI：10.1021/jo00254a026

  日期：1988.9
• KIM, SUNGGAK;KIM, YONG, JIN;AHN, KYO, HAN, TETRAHEDRON LETT., 1983, 24, N 32, 3369-3372
  作者：KIM, SUNGGAK、KIM, YONG, JIN、AHN, KYO, HAN

  DOI：——

  日期：——
• KIM, SUNGGAK;KO, JAE, SUK, SYNTH. COMMUN., 1985, 15, N 7, 603-606
  作者：KIM, SUNGGAK、KO, JAE, SUK

  DOI：——

  日期：——