[EN] HYALURONIC ACID DERIVATIVES AND PROCESSES FOR PREPARING THE SAME<br/>[FR] DERIVES D'ACIDE HYALURONIQUE ET LEURS PROCEDES DE PREPARATION
申请人:LG LIFE SCIENCES LTD
公开号:WO2004022603A1
公开(公告)日:2004-03-18
The present invention provides hyaluronic acid derivatives with hyaluronic acid crosslinked to glycol polymer by amide bonds, including a derivative in which a hyaluronic acid is crosslinked to the free amine group-introduced terminal of a glycol polymer by an amide bond, and a derivative in which a hyaluronic acid is crosslinked to a glycol polymer via a chitosan, and its preparation process. The hyaluronic acid derivatives according to the present invention are biocompatible and have a very high viscoelasticity, and thus can be used in the form of gel, film or thread, for various purposes such as biomaterials for post-operative adhesion-prevention gel, dermal augmentation, correction of facial wrinkles, osteoarthritic viscosupplement, plastic surgery, drug delivery, etc.