(1R,2S)-1-Butyl-2-chloro-cyclopropane | 109125-05-5

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 有机氯化物
• 英文名称: (1R,2S)-1-Butyl-2-chloro-cyclopropane
• 英文别名: (1R,2S)-1-butyl-2-chlorocyclopropane
• CAS: 109125-05-5
• 化学式: C₇H₁₃Cl
• 分子量: 132.633
• InChiKey: OQNANHXSFFTTHF-RQJHMYQMSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  8.0
• 可旋转键数：
  3.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0.0
• 氢给体数：
  0.0
• 氢受体数：
  0.0

反应信息

• 作为产物：
  描述：

  2-butyl-1,1-dichloro-cyclopropane 在 potassium diphenylphosphine 作用下， 以 二甲基亚砜 为溶剂， 反应 1.0h， 生成 (1R,2R)-1-Butyl-2-chloro-cyclopropane 、 (1R,2S)-1-Butyl-2-chloro-cyclopropane
  参考文献：
  名称：

  Stereoselective reduction of gem-dichlorocyclopropanes by potassium diphenylphosphide

  摘要：

  DOI：

  10.1021/jo00226a039

文献信息

• Stereoselective reduction of gem-dichlorocyclopropanes to cis-monochlorocyclopropanes by lithium aluminum hydride in the presence of titanium and zirconium complexes
  作者：U. M. Dzhemilev、R. L. Gaisin、A. A. Turchin、G. A. Tolstikov

  DOI：10.1007/bf00960415

  日期：1991.9

  A versatile stereoselective method is presented for the synthesis of cis-monochlorocyclopropanes by the reduction of dehalogenated alkyl- and aryl-gem-dichlorocyclopropanes in the presence of catalytic quantities of titanium and zirconium complexes.
• Efficient method for the synthesis of monohalocyclopropanes by reduction of gem-dihalocyclopropanes with i-Bu2AlH in the presence of Ti and Zr complexes
  作者：U. M. Dzhemilev、R. L. Gaisin、A. A. Turchin、N. R. Khalikova、I. P. Baikova、G. A. Tolstikov

  DOI：10.1007/bf00961692

  日期：1990.5

  We have investigated the reductive dehalogenation reaction of alkyl and aryl substituted gemdihalocyclopropanes with diisobutyl aluminum hydride in the presence of catalytic amounts of titanium and zirconium complexes. As a result we propose a general method for the synthesis of substituted monohalocyclopropanes and cyclopropanes of various structures. We have also studied the stereochemistry of the reduction.