Pentadecyl-(4-hydroxy-phenyl)-aether | 13036-03-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: Pentadecyl-(4-hydroxy-phenyl)-aether
• 英文别名: 4-Hydroxy-1-pentadecyloxy-benzol；O-Pentadecyl-hydrochinon；4-Pentadecyloxy-phenol；4-Pentadecoxyphenol
• CAS: 13036-03-8
• 化学式: C₂₁H₃₆O₂
• 分子量: 320.516
• InChiKey: BLOVTAIJIZEQIF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.9
• 重原子数：
  23
• 可旋转键数：
  15
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  偶氮苯六氟磷酸盐 、 Pentadecyl-(4-hydroxy-phenyl)-aether 生成 6-Hydroxy-3-pentadecyloxy-azobenzol
  参考文献：
  名称：

  Mehta; Mehta; Thosar, Journal of the Indian Chemical Society, Industrial and News Edition, 1941, vol. 4, p. 170,174

  摘要：

  DOI：

文献信息

• [EN] A PROCESS FOR THE PREPARATION OF TRIAZINE INTERMEDIATES AND A PROCESS FOR THE PREPARATION OF UV ABSORBERS THEREOF<br/>[FR] PROCÉDÉ DE PRÉPARATION D'INTERMÉDIAIRES DE TRIAZINE ET PROCÉDÉ DE PRÉPARATION D'ABSORBEURS UV ASSOCIÉS
  申请人：BASF SE

  公开号：WO2020144093A1

  公开（公告）日：2020-07-16

  The presently claimed invention relates to a novel, highly efficient and general process for the preparation of the triazine intermediates and their use in the preparation of UV absorbers.

  目前所声称的发明涉及一种新颖、高效和通用的三嗪中间体制备过程及其在制备紫外线吸收剂中的应用。
• A PROCESS FOR THE PREPARATION OF TRIAZINE INTERMEDIATES AND A PROCESS FOR THE PREPARATION OF UV ABSORBERS THEREOF
  申请人：BASF SE

  公开号：EP3908633A1

  公开（公告）日：2021-11-17
• Molecules to Enhance Percutaneous Delivery and Methods for Discovery Therefor
  申请人：Mitragotri Samir

  公开号：US20090105260A1

  公开（公告）日：2009-04-23

  An IR spectroscopic technique provides methods for measuring the irritation potential of a formulation and to assess the ability of molecules to enhance the permeability of substances into and through skin using samples comprising stratum corneum. Molecules are screened for their performance as chemical penetration enhancers using a unique in silico procedure that may be applied iteratively in an attempt to generate molecules showing successively higher performance. Both the irritation potential and the ability of the molecule to enhance penetration are considered in the in silico approach. The invention provides specific molecules that may be used in topical or transdermal formulations to improve the delivery of actives. The structures of compounds of the invention include: Formulas (I), (II), (III), (IV), (V), (IV) and analogs thereof.