2-Mercaptochinoxalin-1-oxid | 42826-19-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂萘
• 英文名称: 2-Mercaptochinoxalin-1-oxid
• CAS: 42826-19-7
• 化学式: C₈H₆N₂OS
• 分子量: 178.214
• InChiKey: UNBPIPFGGRHHJB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.16
• 重原子数：
  12.0
• 可旋转键数：
  0.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  39.83
• 氢给体数：
  1.0
• 氢受体数：
  3.0

文献信息

• [EN] LANTHANIDE METAL COMPLEXES USEFUL IN TREATING CANCER<br/>[FR] COMPLEXES MÉTALLIQUES DE LANTHANIDES UTILES DANS LE TRAITEMENT D'UN CANCER
  申请人：AGENCY SCIENCE TECH & RES

  公开号：WO2010114493A1

  公开（公告）日：2010-10-07

  The present invention relates to a compound of formula (I). Provided is also a method of killing a cell that comprises administering the compound of formula (I). Provided is also a method of treating cancer or diabetes in a mammal that comprises administering the compound of formula I and respective pharmaceutical compositions thereof.

  本发明涉及式(I)的化合物。还提供了一种杀死细胞的方法，该方法包括给予式(I)的化合物。还提供了一种在哺乳动物中治疗癌症或糖尿病的方法，该方法包括给予式(I)的化合物及其相应的制药组合物。
• Agents and method for the protection of coatings and wood and other non-living organic substrates from deterioration by micro-organisms
  申请人：JANSSEN PHARMACEUTICA N.V.

  公开号：EP0038109A2

  公开（公告）日：1981-10-21

  The agents protect coatings and wood and other non-living organic materials, in particular textiles, from deterioration by microorganisms. The agents contain at least one compound of the formula wherein X is nitrogen or a CH group and R1 is a radikal of the formula wherein Ar, R and Z are as defined in claim one, or an acid addition salt thereof. The metod provided comprises applying at least one compound as just specified to, or incorporating it in, the material to be protected, in an antimicrobially effective amount.

  这些制剂可保护涂料、木材和其他非生物有机材料，特别是纺织品，免受微生物的侵蚀。药剂中至少含有一种式如下的化合物 其中 X 是氮或 CH 基团，R1 是式中的 Radikal。 其中 Ar、R 和 Z 如权利要求 1 所定义，或其酸加成盐。 本发明提供的方法包括将至少一种上述化合物以有效的抗菌量施用到待保护材料上，或将其加入待保护材料中。
• Water-dilutable wood-preserving liquids
  申请人：JANSSEN PHARMACEUTICA N.V.

  公开号：EP0148526A1

  公开（公告）日：1985-07-17

  A water-dilutable wood-preserving liquid containing from 10% w/w to 80% w/w of a suitable solvent, from 20% w/w to 80% w/w of a suitable solubilizer and from 0.01% w/w to 10% w/w of an azole of formula or an acid-addition salt thereof.

  一种可用水稀释的木材防腐液，含有 10%（重量比）至 80%（重量比）的适当溶剂、 20%（重量比）至 80%（重量比）的适当增溶剂和 0.01%（重量比）至 10%（重量比）的式唑或其酸加成盐。 或其酸加成盐。
• Preservative formulations comprising an oxathiazine and amine oxides
  申请人：JANSSEN PHARMACEUTICA N.V.

  公开号：EP1273234A1

  公开（公告）日：2003-01-08

  The present invention relates to the use of amine oxides to enhance the activity of fungicidal formulations comprising a fungicidal oxathiazine compound. It also relates to formulations comprising a fungicidal oxathiazine compound which is bethoxazin and amine oxides. These formulations are useful for the protection of objects made of wood, thatch or the like, biodegradable material and textiles against deterioration due to the action of fungi.

  本发明涉及使用氧化胺来增强包含杀真菌噁噻嗪化合物的杀真菌制剂的活性。本发明还涉及由杀真菌的噁噻嗪化合物（即贝特嗪）和氧化胺组成的制剂。这些制剂可用于保护木材、茅草或类似材料制成的物体、可生物降解的材料和纺织品，使其免受真菌作用而变质。
• Preservative formulations comprising an oxathiazine and alkoxylated amines
  申请人：JANSSEN PHARMACEUTICA N.V.

  公开号：EP1273233A1

  公开（公告）日：2003-01-08

  The present invention relates to the use of alkoxylated amines to enhance the activity of fungicidal formulations comprising a fungicidal oxathiazine compound which is bethoxazin. It also relates to formulations comprising an oxathiazine compound and alkoxylated amines. These formulations are useful for the protection of objects made of wood, thatch or the like, biodegradable material and textiles against deterioration due to the action of fungi.

  本发明涉及使用烷氧基化胺来增强由杀真菌的噁噻嗪化合物（即贝伐嗪）组成的杀真菌制剂的活性。本发明还涉及由噁噻嗪化合物和烷氧基化胺组成的制剂。这些制剂可用于保护木材、茅草或类似材料制成的物体、可生物降解材料和纺织品，防止因真菌作用而变质。