3-烯丙基-2-[(1E,3Z)-3-(3-烯丙基-1,3-苯并噻唑-2(3H)-亚基)-1-丙烯-1-基]-1,3-苯并噻唑-3-鎓 | 34263-37-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻唑类
• 中文名称: 3-烯丙基-2-[(1E,3Z)-3-(3-烯丙基-1,3-苯并噻唑-2(3H)-亚基)-1-丙烯-1-基]-1,3-苯并噻唑-3-鎓
• 英文名称: 1,3-bis-(3-allyl-benzothiazol-2-yl)-trimethinium ; iodide
• 英文别名: 1,3-Bis-(3-allyl-benzothiazol-2-yl)-trimethinium; Jodid；3-allyl-2-[3-(3-allylbenzothiazol-2(3H)-ylidene)prop-1-enyl]benzothiazolium iodide；(2E)-3-prop-2-enyl-2-[(Z)-3-(3-prop-2-enyl-1,3-benzothiazol-3-ium-2-yl)prop-2-enylidene]-1,3-benzothiazole;iodide
• CAS: 34263-37-1
• 化学式: C₂₃H₂₁N₂S₂*I
• 分子量: 516.47
• InChiKey: YPWICDUMOAZDQH-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  3.03
• 重原子数：
  28
• 可旋转键数：
  6
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.09
• 拓扑面积：
  60.7
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• [EN] DIFFERENTIATION MODULATING AGENTS AND USES THEREFOR<br/>[FR] AGENTS DE MODULATION DE LA DIFFERENCIATION ET UTILISATIONS ASSOCIEES
  申请人：UNIV QUEENSLAND

  公开号：WO2005065686A1

  公开（公告）日：2005-07-21

  This invention discloses methods and agents for modulating the differentiation potential and/or proliferation of preadipocytes. More particularly, the present invention discloses methods and agents for modulating a fibroblast growth factor (FGF) signalling pathway, especially the FGF-1 or FGF-2 signalling pathway, for treating or preventing adiposity-related conditions including, but not limited to, obesity, lipoma and lipomatosis.

  该发明揭示了调节前脂肪细胞分化潜能和/或增殖的方法和药剂。更具体地，本发明揭示了调节成纤维细胞生长因子（FGF）信号通路的方法和药剂，特别是FGF-1或FGF-2信号通路，用于治疗或预防与脂肪相关的疾病，包括但不限于肥胖、脂肪瘤和脂肪增生。
• METHODS AND COMPOSITIONS FOR DETECTING POLYNUCLEOTIDES
  申请人：Investigen, Inc.

  公开号：EP2010677A2

  公开（公告）日：2009-01-07
• Differentiation modulating agents and uses therefor
  申请人：Prins Bernhard Johannes

  公开号：US20050282733A1

  公开（公告）日：2005-12-22

  The present invention is directed to methods and agents for modulating the differentiation potential and/or proliferation of preadipocytes. More particularly, the present invention discloses methods and agents for modulating a fibroblast growth factor (FGF) signaling pathway, especially the FGF-1 or FGF-2 signaling pathway, for treating or preventing adiposity-related conditions including, but not limited to, obesity, lipoma, lipomatosis, cachexia or lipodystrophy or the loss of adipose tissue in trauma or atrophic conditions.
• Methods and compositions for detecting polynucleotides
  申请人：Bupp Robert Charles

  公开号：US20070231821A1

  公开（公告）日：2007-10-04

  Methods of determining the presence or amount of a target polynucleotide in a sample are provided. A sample that contains a target polynucleotide, a polynucleotide that may include nucleic acid analogs and that is complementary to a target nucleic acid sequence of the target polynucleotide, and a dye for which the rate of change in an optical property is different in the presence and absence of a target polynucleotide/polynucleotide hybrid are combined to produce a reaction mixture. The rate of change in an optical property of the dye in the reaction mixture is compared to a reference value characteristic of the rate of change in the optical property of the dye in a similar reaction mixture containing a known amount of a polynucleotide/polynucleotide hybrid to determine a relative rate of change in the optical property. The relative rate of change in the optical property of dye in the reaction mixture is correlated with the presence or amount of the specified target polynucleotide in the sample.
• METHODS AND COMPOSITIONS FOR RAPID LIGHT-ACTIVATED ISOLATION AND DETECTION OF ANALYTES
  申请人：Holmes-Davis Rachel Anne

  公开号：US20080220436A1

  公开（公告）日：2008-09-11

  The present invention relates to novel methods for isolating a target molecule from a sample suspected of containing the target molecule. The methods of the present invention utilize solid substrates as a means for capturing, separating, and releasing target molecules, such as chemical or biological compounds. The present invention is specifically directed to novel approaches for capturing, separating and releasing such target molecules.