7-hexyloxy-2-hydroxynaphthalene | 1096905-66-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 7-hexyloxy-2-hydroxynaphthalene
• 英文别名: 7-Hexoxynaphthalen-2-ol
• CAS: 1096905-66-6
• 化学式: C₁₆H₂₀O₂
• mdl: MFCD11540402
• 分子量: 244.334
• InChiKey: ZEOMTBNJODVFEY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.1
• 重原子数：
  18
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.375
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  7-hexyloxy-2-hydroxynaphthalene 、 2-(4-((6-bromohexyl)oxy)phenyl)-5-(4'-(octyloxy)-[1,1'-biphenyl]-4-yl)-1,3,4-oxadiazole 在 potassium carbonate 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 25.0h， 以82%的产率得到27-6N6Ox
  参考文献：
  名称：

  Synthesis and Optical Properties of Luminescent Naphthalene-based Liquid Crystals

  摘要：

  Luminescent naphthalene-based liquid crystals were newly synthesized and changes of the luminescent color through the phase transitions were characterized. We prepared the compounds by combining naphthalene and known mesogenic cores, oxadiazole and fluorocyanobiphenyl, using methylene spacers. Both oxadiazole-naphthalene and fluorocyanobiphenyl-naphthalene series showed bluish luminescence in all phases. Among them, the emission peaks of 3-fluoro-4-cyano-4 '-[8-(6-hexyloxy-2-naphthyloxy)octyloxy]biphenyl in the liquid crystal and isotropic liquid states showed significant red shifts compared to that in the crystal state, which was due to specific interaction between the electron rich naphthalene and electron deficient fluorocyanobiphenyl cores.

  DOI：

  10.1080/15421400802219254
• 作为产物：
  描述：

  溴己烷 、 2,7-二羟基萘 在 potassium carbonate 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 生成 7-hexyloxy-2-hydroxynaphthalene
  参考文献：
  名称：

  Synthesis and Optical Properties of Luminescent Naphthalene-based Liquid Crystals

  摘要：

  Luminescent naphthalene-based liquid crystals were newly synthesized and changes of the luminescent color through the phase transitions were characterized. We prepared the compounds by combining naphthalene and known mesogenic cores, oxadiazole and fluorocyanobiphenyl, using methylene spacers. Both oxadiazole-naphthalene and fluorocyanobiphenyl-naphthalene series showed bluish luminescence in all phases. Among them, the emission peaks of 3-fluoro-4-cyano-4 '-[8-(6-hexyloxy-2-naphthyloxy)octyloxy]biphenyl in the liquid crystal and isotropic liquid states showed significant red shifts compared to that in the crystal state, which was due to specific interaction between the electron rich naphthalene and electron deficient fluorocyanobiphenyl cores.

  DOI：

  10.1080/15421400802219254

文献信息

• Pd-Catalyzed Formal [3+3] Annulation of Benzylic <i>gem</i>-Diacetates: Synthesis of Various (Hetero)Arene-Fused Benzo[<i>f</i>]chromenes
  作者：Prashant Kumar、Mrudula M. Nikam、S. S. V. Ramasastry

  DOI：10.1021/acs.organomet.2c00472

  日期：——

  Unlike that of benzyl acetates, the chemistry of benzyl gem-diacetates is rarely explored under metal catalysis. Here, we describe the first palladium-catalyzed cascade annulative allylic alkylation of benzylic gem-diacetates to access complex analogues of (hetero)arene-fused benzo[f]chromenes, which find relevance in medicinal chemistry and materials science. This synthetic feat has been achieved

  与乙酸苄酯不同，偕二乙酸苄酯的化学性质很少在金属催化下进行研究。在这里，我们描述了第一个钯催化的苄基宝石二乙酸酯的级联环烯丙基烷基化，以获得（杂）芳烃稠合苯并[ f ]色烯的复杂类似物，这在药物化学和材料科学中具有相关性。这一合成壮举是通过在中性条件下容易获得的（杂）芳基偕二乙酸酯和容易获得的2-萘酚的正式[3+3]杂环化来实现的。还进行了详细的机制研究和综合阐述。