3',6'-dihydroxy-1',8'-dimethyl-spiro[phthalan-1,9'-xanthen]-3-one | 100770-41-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: 3',6'-dihydroxy-1',8'-dimethyl-spiro[phthalan-1,9'-xanthen]-3-one
• 英文别名: 3',6'-Dihydroxy-1',8'-dimethyl-spiro[phthalan-1,9'-xanthen]-3-on
• CAS: 100770-41-0
• 化学式: C₂₂H₁₆O₅
• 分子量: 360.366
• InChiKey: WKSQNBXYBULEPP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.28
• 重原子数：
  27.0
• 可旋转键数：
  0.0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  75.99
• 氢给体数：
  2.0
• 氢受体数：
  5.0

反应信息

• 作为产物：
  描述：

  3,5-dibromo-2'-carboxy-2,4-dihydroxybenzophenone 在 磷酸酐 、 zinc(II) chloride 作用下， 生成 3',6'-dihydroxy-1',8'-dimethyl-spiro[phthalan-1,9'-xanthen]-3-one
  参考文献：
  名称：

  Meyer,R.; Meyer,H., Chemische Berichte, 1896, vol. 29, p. 2624

  摘要：

  DOI：

文献信息

• Ti(IV) doping: An effective strategy to boost Lewis acidic performance of ZnO catalyst in fluorescein dye synthesis
  作者：Nirajkumar H. Jadhav、Dnyaneshwar R. Shinde、Sachin S. Sakate、Nishant K. Rasal、Ramdas A. Pawar

  DOI：10.1016/j.catcom.2018.11.008

  日期：2019.2

  Zn1-xTixO NPS were efficiently synthesized using a simple solution free mechanochemical method. The synthesized ZnO and Ti(IV)-doped ZnO catalysts are exhibited polycrystallinity, a hexagonal crystal structure, and roughly spherical agglomerates. The surface areas of the Zn1-xTixO catalysts were positively correlated with the doping percentage of Ti(IV), which also enhanced the Lewis acidity of the NPs. The catalysts exhibited excellent activity during the synthesis of fluorescein dyes. This methodology was also extended to sulfone-fluorescein dye synthesis.
• Orndorff; Allen, Journal of the American Chemical Society, 1915, vol. 37, p. 1248
  作者：Orndorff、Allen

  DOI：——

  日期：——