N-vanillyl-non-2-enamide | 85223-59-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: N-vanillyl-non-2-enamide
• 英文别名: Δ^α-Nonensaeure-vanillylamid；Octen-(1)-carbonsaeure-(1)-vanillylamid；N-Vanillyl-non-2-enamid；(E)-N-[(4-hydroxy-3-methoxyphenyl)methyl]non-2-enamide
• CAS: 85223-59-2
• 化学式: C₁₇H₂₅NO₃
• 分子量: 291.39
• InChiKey: CZSCSWGNICCXIQ-CMDGGOBGSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  21
• 可旋转键数：
  9
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.47
• 拓扑面积：
  58.6
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• Formulations for the treatment of pain
  申请人：Grünenthal GmbH

  公开号：US10576047B2

  公开（公告）日：2020-03-03

  Formulations and methods are provided for the treatment of pain, and neuropathic pain in particular. The formulations are eutectic mixtures of a capsaicinoid and a local anesthetic agent and/or an anti-pruritic agent.

  提供了治疗疼痛，特别是神经性疼痛的制剂和方法。这些制剂是辣椒素与局部麻醉剂和/或抗瘙痒剂的共晶混合物。
• FORMULATIONS COMPRISING A CAPSAICINOID, A LOCAL ANESTHETIC AND/OR AN ANTIPRURITIC AGENT FOR THE TREATMENT OF PAIN
  申请人：SRI International

  公开号：EP1763370A1

  公开（公告）日：2007-03-21
• FORMULATIONS COMPRISING CAPSAICIN, A LOCAL ANESTHETIC AND/OR AN ANTIPRURITIC AGENT FOR THE TREATMENT OF PAIN
  申请人：NeurogesX Inc.

  公开号：EP1763370B1

  公开（公告）日：2015-04-29
• FORMULATIONS FOR THE TREATMENT OF PAIN
  申请人：Maniar Manoj

  公开号：US20120238624A1

  公开（公告）日：2012-09-20

  Formulations and methods are provided for the treatment of pain, and neuropathic pain in particular. The formulations are eutectic mixtures of a capsaicinoid and a local anesthetic agent and/or an anti-pruritic agent.
• FORMULATION FOR THE TREATMENT OF PAIN
  申请人：Acorda Therapeutics, Inc.

  公开号：US20150250745A1

  公开（公告）日：2015-09-10

  Formulations and methods are provided for the treatment of pain, and neuropathic pain in particular. The formulations are eutectic mixtures of a capsaicinoid and a local anesthetic agent and/or an anti-pruritic agent.