2-(3-cyclopropyl-1,4-dimethyl-1H-pyrazolo[3,4-b]pyridin-6-yloxy)-N-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)acetamide | 1312947-98-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 四氢化萘
• 英文名称: 2-(3-cyclopropyl-1,4-dimethyl-1H-pyrazolo[3,4-b]pyridin-6-yloxy)-N-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)acetamide
• 英文别名: 2-(3-cyclopropyl-1,4-dimethylpyrazolo[3,4-b]pyridin-6-yl)oxy-N-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)acetamide
• CAS: 1312947-98-0
• 化学式: C₂₄H₂₈N₄O₃
• 分子量: 420.511
• InChiKey: IAPUCOXASIDURY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  31
• 可旋转键数：
  6
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  78.3
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• [EN] DISUBSTITUTED HETEROARYL-FUSED PYRIDINES<br/>[FR] PYRIDINES ACCOLÉES À DI-SUBSTITUTION HÉTÉROARYLE
  申请人：NOVARTIS AG

  公开号：WO2011076744A1

  公开（公告）日：2011-06-30

  The invention relates to compound of the formula (I') in which the substituents are as defined in the specification; in free form or in salt form; to its preparation, to its use as medicament and to medicaments comprising it.

  这项发明涉及公式(I')的化合物，其中取代基如规范中所定义；以自由形式或盐形式存在；其制备方法，其作为药物的用途以及包含它的药物。
• DISUBSTITUTED HETEROARYL-FUSED PYRIDINES
  申请人：Babiger Sangamesh

  公开号：US20120258973A1

  公开（公告）日：2012-10-11

  The invention relates to compound of the formula (I′) in which the substituents are as defined in the specification; in free form or in salt form; to its preparation, to its use as medicament and to medicaments comprising it.

  这项发明涉及式(I′)的化合物，其中取代基如规范中所定义；以自由形式或盐形式存在；其制备，其作为药物的用途以及包含它的药物。
• Preparation and utility of substituted amphetamines
  申请人：Gant G. Thomas

  公开号：US20080045588A1

  公开（公告）日：2008-02-21

  Provided herein are substituted amphetamines, processes of preparation and pharmaceutical compositions thereof. Also provided are methods of their use for the treatment and/or management of trauma associated with a terminal disease, a post-traumatic-stress-disorder, or a psychological disorder.
• US8742106B2
  申请人：——

  公开号：US8742106B2

  公开（公告）日：2014-06-03