3-(2-furyl)pyrazolo[3,4-d]pyrimidine-4-ylamine | 358979-46-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡唑并嘧啶类
• 英文名称: 3-(2-furyl)pyrazolo[3,4-d]pyrimidine-4-ylamine
• 英文别名: 3-(furan-2-yl)pyrazolo[3,4-d]pyrimidine-4-ylamine；3-(furan-2-yl)-2H-pyrazolo[3,4-d]pyrimidin-4-amine
• CAS: 358979-46-1
• 化学式: C₉H₇N₅O
• 分子量: 201.187
• InChiKey: QQWHQZOTBLYYDS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  15
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  93.6
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• TMLEVELING METHODS
  申请人：Epoch Biosciences, Inc.

  公开号：US20030224359A1

  公开（公告）日：2003-12-04

  Modified oligonucleotides are provided containing bases selected from unsubstituted and 3-substituted pyrazolo[3,4-d]pyrimidines and 5-substituted pyrimidines, and optionally have attached minor groove binders and reporter groups.

  提供了改性寡核苷酸，其中包含选择自未取代和3-取代的吡唑并[3,4-d]嘧啶和5-取代嘧啶的碱基，并且可选择附加次级沟结合剂和报告分子。
• Tm leveling compositions
  申请人：Dempcy O. Robert

  公开号：US20060003349A1

  公开（公告）日：2006-01-05

  Modified oligonucleotides are provided containing bases selected from unsubstituted and 3-substituted pyrazolo[3,4-d]pyrimidines and 5-substituted pyrimidines, and optionally have attached minor groove binders and reporter groups.

  提供了修饰的寡核苷酸，其中包含从未置换和3-置换的吡唑并[3,4-d]嘧啶和5-置换的嘧啶中选择的碱基，并且可选择附加小沟结合剂和报告基团。
• Systems and methods for predicting oligonucleotide melting temperature (TmS)
  申请人：Epoch Biosciences, Inc.

  公开号：US20030235822A1

  公开（公告）日：2003-12-25

  Software systems and methods for predicting the melting temperature (T m ) and other characteristics of oligonucleotides, including modified oligonucleotides. Modified oligonucleotides are provided containing bases selected from unsubstituted and 3-substituted pyrazolo[3,4-d]pyrimidines and 5-substituted pyrimidines, and optionally have attached minor groove binders and reporter groups.

  该软件系统和方法可以预测寡核苷酸的熔点（Tm）和其他特性，包括修饰的寡核苷酸。提供的修饰的寡核苷酸包含从未取代和3-取代的吡唑并[3,4-d]嘧啶和5-取代的嘧啶选择的碱基，并且可以附有小沟结合剂和报告基团。
• MODIFIED OLIGONUCLEOTIDES FOR MISMATCH DISCRIMINATION
  申请人：Dempcy O. Robert

  公开号：US20060009628A1

  公开（公告）日：2006-01-12

  Modified oligonucleotides are provided containing bases selected from unsubstituted and 3-substituted pyrazolo[3,4-d]pyrimidines and 5-substituted pyrimidines, and optionally have attached minor groove binders and reporter groups.

  提供了修饰寡核苷酸，其中包含从未取代的和3-取代的吡唑并[3,4-d]嘧啶和5-取代的嘧啶选择的碱基，并且可以附加小沟结合剂和报告基团。
• TM leveling methods
  申请人：Dempcy O. Robert

  公开号：US20050075491A1

  公开（公告）日：2005-04-07

  Modified oligonucleotides are provided containing bases selected from unsubstituted and 3-substituted pyrazolo[3,4-d]pyrimidines and 5-substituted pyrimidines, and optionally have attached minor groove binders and reporter groups.

  提供了一些修饰寡核苷酸，其中包含从未取代的和3-取代的吡唑并[3,4-d]嘧啶和5-取代嘧啶中选择的碱基，并且可选择地附有次级沟结合剂和报告基团。