perfluoro n-butyldecalin | 118914-93-5

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 卤代烷
• 英文名称: perfluoro n-butyldecalin
• 英文别名: Perfluorodecahydro-1-(perfluorobutyl)naphthalene；1,1,2,2,3,3,4,4,4a,5,5,6,6,7,7,8,8a-heptadecafluoro-8-(1,1,2,2,3,3,4,4,4-nonafluorobutyl)naphthalene
• CAS: 118914-93-5
• 化学式: C₁₄F₂₆
• 分子量: 662.112
• InChiKey: KOQYZEXXQFIMRZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.3
• 重原子数：
  40
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  26

文献信息

• NANOEMULSIONS AND USE THEREOF AS CONTRAST AGENTS
  申请人：GUERBET

  公开号：US20140234223A1

  公开（公告）日：2014-08-21

  The invention relates to an oil-in-water nanoemulsion for MRI, including: an aqueous phase, a fluorinated phase including at least one fluorinated oil, a surfactant at the interface between the aqueous and fluorinated phases, the surfactant comprising: at least one amphiphilic targeting ligand, at least one amphiphilic lipid, and at least one diblock or triblock fluorophilic compound, as well as to the use thereof as a contrast agent.

  这项发明涉及一种用于磁共振成像的油包水纳米乳液，包括： 水相， 含有至少一种氟化油的氟化相， 位于水相和氟化相之间的表面活性剂，所述表面活性剂包括： 至少一种两性靶向配体， 至少一种两性脂质，以及 至少一种二嵌段或三嵌段亲氟化合物， 以及将其用作对比剂的用途。
• Perfluorinated butyl derivative compounds
  申请人：AIR PRODUCTS AND CHEMICALS, INC.

  公开号：EP0304809A1

  公开（公告）日：1989-03-01

  Novel compositions of matter are disclosed having the formula wherein the carbon rings are fully fluorinated to remove all hydrogens and olefinic character. The compositions have utility as heat transfer agents, hydraulic fluids, vapor phase soldering fluids, gas (O₂, N₂, CO₂, H₂, etc.) transport agents, such as in biological and medical fields, as well as utility as burn-in test fluid.

  公开了具有以下式子的新型物质组合物 其中的碳环已完全氟化，去除了所有的氢和烯烃特性。这些组合物可用作热传导剂、液压油、气相焊接液、气体（O₂、N₂、CO₂、H₂等）输送剂，如生物和医疗领域，还可用作烧损测试液。
• Interstitial administration of perfluorchemical emulsions for reoxygenation of hypoxic tumor cells
  申请人：AIR PRODUCTS AND CHEMICALS, INC.

  公开号：EP0279379B1

  公开（公告）日：1992-11-04
• VISCOELASTIC COMPOSITIONS OF FLUORINATED ORGANIC COMPOUNDS
  申请人：ALLIANCE PHARMACEUTICAL CORP.

  公开号：EP0722313B1

  公开（公告）日：1999-05-12
• REVERSE GELS COMPRISING A CONTINUOUS FLUORINATED PHASE
  申请人：ALLIANCE PHARMACEUTICAL CORPORATION

  公开号：EP0841896B1

  公开（公告）日：2002-11-13