3-甲基六氢-1-苯并呋喃-2(3H)-酮 | 2205-25-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并呋喃
• 中文名称: 3-甲基六氢-1-苯并呋喃-2(3H)-酮
• 英文名称: 3-methyl-hexahydro-benzofuran-2-one
• 英文别名: 3-Methylhexahydro-1-benzofuran-2(3H)-one；3-methyl-3a,4,5,6,7,7a-hexahydro-3H-1-benzofuran-2-one
• CAS: 2205-25-6
• 化学式: C₉H₁₄O₂
• 分子量: 154.209
• InChiKey: YBWKITXSXPBILI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  11
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 海关编码：
  2932209090

反应信息

• 作为反应物：
  描述：

  3-甲基六氢-1-苯并呋喃-2(3H)-酮 在 sodium hydroxide 、 magnesium sulfate 作用下， 生成 2-(2-oxo-cyclohexyl)-propionic acid
  参考文献：
  名称：

  McRae; Charlesworth; Alexander, Canadian Journal of Research, Section B: Chemical Sciences, 1943, vol. 21, p. 1,9

  摘要：

  DOI：
• 作为产物：
  描述：

  2-(1'-hydroxycyclohexyl)propionic acid 以64%的产率得到
  参考文献：
  名称：

  WATANABE SHOJI; FUJITA TSUTOMU; SUGA KYOICHI; ISOBE TOSHIO; MIURA TOSHIRO+, YUKAGAKU, YUKAGAKU, J. JAR. OIL CHEM. SOS., 1980, 29, NO 1, 43-48

  摘要：

  DOI：

文献信息

• Method of repelling insects
  申请人：COULSTON INTERNATIONAL CORPORATION

  公开号：EP0167265A1

  公开（公告）日：1986-01-08

  Compositions containing certain bicyclic lactones and having insect repellent properties are disclosed. Such compositions comprise a compound of the formula: or the corresponding unsaturated compound thereof having the formula: wherein R, R', R" and R''' each are lower alkyl or hydrogen; wherein y is an integer from 1-3, and x and z each are 0 or 1, with the proviso that y is 1 or 2 when x is 1; and a carrier. A method of using such a repellent composition to repel an insect from a situs comprises applying to such situs an effective amount of the composition, with or without the carrier, and thereby repelling the insect from the situs.

  本发明公开了含有某些双环内酯并具有昆虫驱避特性的组合物。 这种组合物包括式中的化合物：或其相应的不饱和化合物，其式为： 其中R、R'、R "和R'''各自为低级烷基或氢；其中y为1-3的整数，x和z各自为0或1，但当x为1时，y为1或2；以及载体。 使用这种驱避组合物来驱赶昆虫的方法包括将有效量的组合物（含或不含载体）施用于该部位，从而将昆虫从该部位驱赶出去。
• Glucagon-like peptide 1 modulator and uses thereof
  申请人：Academia Sinica

  公开号：US10392357B2

  公开（公告）日：2019-08-27

  Disclosed herein are novel glucagon-like peptide-1 (GLP-1) modulators and their uses in manufacturing medicaments for the treatment and/or prophylaxis of diseases and/or disorders associated with hyperglycemia.

  本文公开了新型胰高血糖素样肽-1（GLP-1）调节剂及其在制造治疗和/或预防与高血糖有关的疾病和/或紊乱的药物中的用途。
• The First Stereoselective Palladium-Catalyzed Cyclocarbonylation of β,γ-Substituted Allylic Alcohols
  作者：Melanie Brunner、Howard Alper

  DOI：10.1021/jo9702709

  日期：1997.10.1

  beta,gamma-Substituted allylic alcohols react with CO in the presence of catalytic quantities of palladium acetate and 1,4-bis(diphenylphosphino)butane affording alpha,beta-substituted-gamma-butyrolactones in 42-85% isolated yields. The complete stereoselectivity observed in some cases is a significant feature of the lactonization reaction, with (E)-allylic alcohols affording trans-disubstituted lactones. Depending on the structure of the allylic alcohol used in the cyclocarbonylation reaction, the formation of the corresponding alkene or the beta,gamma-unsaturated carboxylic acid was observed as a side or the principal reaction.
• Charlesworth; McRae; MacFarlane, Canadian Journal of Research, Section B: Chemical Sciences, 1943, vol. 21, p. 55,60
  作者：Charlesworth、McRae、MacFarlane

  DOI：——

  日期：——
• CLIVE, D. L. J.;BEAULIEU, P. L., J. CHEM. SOC. CHEM. COMMUN., 1983, N 6, 307-309
  作者：CLIVE, D. L. J.、BEAULIEU, P. L.

  DOI：——

  日期：——