3-Methyl-2-vinylbenzothiophen | 69994-61-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻吩类
• 英文名称: 3-Methyl-2-vinylbenzothiophen
• 英文别名: 3-methyl-2-vinyl-benzo[b]thiophene；2-Ethenyl-3-methyl-1-benzothiophene
• CAS: 69994-61-2
• 化学式: C₁₁H₁₀S
• 分子量: 174.266
• InChiKey: OWTMBBXXUKGOGI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.09
• 拓扑面积：
  28.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  3-Methyl-2-vinylbenzothiophen 、 四氰基乙烯 以45%的产率得到
  参考文献：
  名称：

  CHERRY W. H.; CRAIG J. T.; PORTER Q. N., AUSTRAL. J. CHEM. 1979, 32, NO 1, 133-143

  摘要：

  DOI：
• 作为产物：
  描述：

  2-溴-3-甲基苯并[b]噻吩 以54%的产率得到
  参考文献：
  名称：

  CHERRY W. H.; CRAIG J. T.; PORTER Q. N., AUSTRAL. J. CHEM. 1979, 32, NO 1, 133-143

  摘要：

  DOI：

文献信息

• ORGANIC ELECTROLUMINESCENCE DEVICE AND AMINE COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE
  申请人：Samsung Display Co., Ltd.

  公开号：US20210175430A1

  公开（公告）日：2021-06-10

  An organic electroluminescence device includes a first electrode, a second electrode facing the first electrode, and a plurality of organic layers between the first electrode and the second electrode, wherein at least one of the plurality of organic layers includes an amine compound, the amine compound includes a central nitrogen atom, a carbazole group substituted to the central nitrogen atom, and a dibenzoselenophene group substituted to the central nitrogen atom, and a nitrogen atom of the carbazole group is substituted with a substituted or unsubstituted aryl group or a substituted or unsubstituted heteroaryl group. The organic electroluminescence device thereby has high efficiency and long-life.

  一种有机电致发光器件包括第一电极，面向第一电极的第二电极，以及位于第一电极和第二电极之间的多个有机层，其中多个有机层中至少有一层包括胺化合物，该胺化合物包括中心氮原子、取代于中心氮原子的碳酰胺基团和取代于中心氮原子的二苯硒吩基团，碳酰胺基团的氮原子被取代为取代或未取代的芳基团或取代或未取代的杂环芳基团。因此，该有机电致发光器件具有高效率和长寿命。
• Novel piperidine derivative
  申请人：Ban Hitoshi

  公开号：US20070078120A1

  公开（公告）日：2007-04-05

  The invention provides a compound of the following formula (1): wherein m, n, and p are independently an integer of 0-4, provided 3≦m+n≦8; X is nitrogen atom or a group of the formula: C—R 15 ; Y is a substituted or unsubstituted aromatic group, etc.; R 15 , R 1 , R 2 , R 3 , R 4 , R 5 , R 6 and R 7 are hydrogen atom, a substituted or unsubstituted alkyl group, etc.; and Z is hydrogen atom, cyano group, etc., or a prodrug thereof, or a pharmaceutically acceptable salt thereof, which exhibits an action for enhancing LDL receptor expression, and is useful as a medicament for treating hyperlipidemia, atherosclerosis, etc.

  本发明提供了以下式(1)的化合物：其中m，n和p分别是0-4的整数，满足3≦m+n≦8；X是氮原子或式：C—R15的基团；Y是取代或未取代的芳香基团等；R15，R1，R2，R3，R4，R5，R6和R7是氢原子，取代或未取代的烷基等；Z是氢原子，氰基等，或其前药，或其药学上可接受的盐，具有增强LDL受体表达的作用，并且可用作治疗高脂血症，动脉粥样硬化等药物。
• Piperidine derivatives having ccr3 antagonism
  申请人：Matsumoto Yoshiyuki

  公开号：US20070032525A1

  公开（公告）日：2007-02-08

  The invention provides low molecular compounds having activity which inhibits binding of CCR3 ligands to CCR3 on target cells, i.e. CCR3 antagonists. The invention also provides compounds represented by formula (I) below, pharmaceutically acceptable acid adducts thereof, or pharmaceutically acceptable C 1 -C 6 alkyl adducts thereof, as well as pharmaceutical compositions comprising them as effective ingredients, which are useful for treatment or prevention of diseases associated with CCR3, such as asthma and allergic rhinitis.

  本发明提供了具有抑制CCR3配体结合到靶细胞CCR3的活性的低分子化合物，即CCR3拮抗剂。本发明还提供了由下式（I）表示的化合物，其药学上可接受的酸加合物或药学上可接受的C1-C6烷基加合物，以及包含它们作为有效成分的制药组合物，用于治疗或预防与CCR3相关的疾病，例如哮喘和过敏性鼻炎。
• ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME
  申请人：Rohm And Haas Electronic Materials Korea Ltd.

  公开号：EP3201200B1

  公开（公告）日：2019-05-22
• ORGANIC METAL COMPOUND, ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE HAVING THE COMPOUND
  申请人：LG DISPLAY CO., LTD.

  公开号：US20220209140A1

  公开（公告）日：2022-06-30

  The present disclosure relates to an organic metal compound having the following structure of Formula 1, an organic light emitting diode (OLED) and an organic light emitting device that includes the organic metal compound. The OLED and the organic light emitting device including the organic metal compound can improve their luminous efficiency, luminous color purity and lifespan. |r(L A ) m (L B ) n [Formula 1]