rel-(1R,2S)-1-Amino-1,2,3,4-tetrahydro-5-methoxy-4,4-dimethyl-2-(trifluoromethyl)-2-naphthalenol | 1048104-81-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 四氢化萘
• 英文名称: rel-(1R,2S)-1-Amino-1,2,3,4-tetrahydro-5-methoxy-4,4-dimethyl-2-(trifluoromethyl)-2-naphthalenol
• 英文别名: (1S,2R)-1-amino-5-methoxy-4,4-dimethyl-2-(trifluoromethyl)-1,3-dihydronaphthalen-2-ol
• CAS: 1048104-81-9
• 化学式: C₁₄H₁₈F₃NO₂
• 分子量: 289.29
• InChiKey: KOSFEZVRXBRJKT-WCQYABFASA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  20
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  55.5
• 氢给体数：
  2
• 氢受体数：
  6

文献信息

• Tetrahydronaphthalenylamides, a process for their production and their use as anti-inflammatory agents
  申请人：Bayer Schering Pharma Aktiengesellschaft

  公开号：EP1958934A1

  公开（公告）日：2008-08-20

  The present invention relates to the compounds of formula I, processes for their production and their use as anti-inflammatory agents.

  本发明涉及公式I的化合物，其制备过程以及作为抗炎剂的用途。
• TETRAHYDRONAPHTHALENYLAMIDES, A PROCESS FOR THEIR PRODUCTION AND THEIR USE AS ANTI-INFLAMMATORY AGENTS
  申请人：BERGER Markus

  公开号：US20080200519A1

  公开（公告）日：2008-08-21

  The present invention relates to the compounds of formula I, processes for their production and their use as anti-inflammatory agents.

  本发明涉及式I的化合物，其生产过程及其作为抗炎剂的用途。