N,N-di-n-propyldopamine hydrochloride | 67482-71-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: N,N-di-n-propyldopamine hydrochloride
• 英文别名: 4-[2-(dipropylamino)ethyl]benzene-1,2-diol;hydrochloride
• CAS: 67482-71-7
• 化学式: C14H24ClNO2
• 分子量: 273.8
• InChiKey: NVPSPSIWNWLBQC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.18
• 重原子数：
  18
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  43.7
• 氢给体数：
  3
• 氢受体数：
  3

文献信息

• METHODS FOR TREATING NEUROLOGICAL DISORDERS OR DAMAGE
  申请人：Tyers Mike

  公开号：US20090076019A1

  公开（公告）日：2009-03-19

  A clonogenic neurosphere assay is described that carries out high throughput screens (HTS) to identify potent and/or selective modulators of proliferation, differentiation and/or renewal of neural precursor cells, neural progenitor cells and/or self-renewing and multipotent neural stem cells (NSCs). Compositions comprising the identified modulators and methods of using the modulators and compositions, in particular to treat neurological disorders (e.g. brain or CNS cancer) or damage are also disclosed.