JC049 | 1258064-07-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: JC049
• 英文别名: N-[(3,4-dihydroxyphenyl)methyl]undecanamide
• CAS: 1258064-07-1
• 化学式: C₁₈H₂₉NO₃
• 分子量: 307.433
• InChiKey: NOVGTOGSWXEVAU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  22
• 可旋转键数：
  11
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.61
• 拓扑面积：
  69.6
• 氢给体数：
  3
• 氢受体数：
  3

文献信息

• NOVEL USES
  申请人：Richards Mark

  公开号：US20120083532A1

  公开（公告）日：2012-04-05

  The present invention relates to the use of a compound represented by the general formula (I), and pharmaceutically acceptable salts thereof, wherein: n is an integer from 2 to 5; p is an integer from 0 to 4; R1 is selected from the group consisting of a hydroxyl group, an alkoxy group, a thiol group, a thioether group, and an amino group, wherein at least two of R 1 is a hydroxyl group, a thiol group or an amino group, with the proviso that wherein n is 2, R 1 is not on the carbon-2 position and the carbon-5 position of the phenyl group; R 2 and R 3 are independently a methylene group or a nucleophile, with the proviso that at least one of R 2 and R 3 is a nucleophile group; Z is an oxygen (O) atom or sulfur (S) atom; T is hydrogen or an optionally substituted aliphatic group; in the manufacture of a medicament for treating a patient in need of cell therapy.
• US8703822B2
  申请人：——

  公开号：US8703822B2

  公开（公告）日：2014-04-22
• [EN] NOVEL USES<br/>[FR] NOUVELLES UTILISATIONS
  申请人：NANYANG POLYTECHNIC

  公开号：WO2010144059A2

  公开（公告）日：2010-12-16

  The present invention relates to the use of a compound represented by the general formula (I), and pharmaceutically acceptable salts thereof, wherein : n is an integer from 2 to 5; p is an integer from 0 to 4; R1 is selected from the group consisting of a hydroxyl group, an alkoxy group, a thiol group, a thioether group, and an amino group, wherein at least two of R1 is a hydroxyl group, a thiol group or an amino group, with the proviso that wherein n is 2, R1 is not on the carbon-2 position and the carbon-5 position of the phenyl group; R2 and R3 are independently a methylene group or a nucleophile, with the proviso that at least one of R2 and R3 is a nucleophile group; Z is an oxygen (O) atom or sulfur (S) atom; T is hydrogen or an optionally substituted aliphatic group; in the manufacture of a medicament for treating a patient in need of cell therapy.