2-methyl-1,2-dihydroquinazolin-4(3)-one | 1216761-48-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂萘
• 英文名称: 2-methyl-1,2-dihydroquinazolin-4(3)-one
• 英文别名: 3-Amino-2-methyl-1,2-dihydroquinazolin-4-one
• CAS: 1216761-48-6
• 化学式: C₉H₁₁N₃O
• 分子量: 177.206
• InChiKey: CIWQDFIRBCPTSL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  13
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  58.4
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2-methyl-1,2-dihydroquinazolin-4(3)-one 、 苯甲酰氯 在 三乙胺 作用下， 以 氯仿 为溶剂， 以55%的产率得到3-benzoylamino-2-methyl-1,2-dihydroquinazolin-4(3H)-one
  参考文献：
  名称：

  Anthranoylhydrazones of aliphatic aldehydes and their cyclization to quinazolin-4-one derivatives

  摘要：

  The isomeric transition of 2-aminobenzoylhydrazones of aliphatic aldehydes 2-H2NC6H4CONHN=CHAlk (Alk = Me, Et, Pr, Bu) in chloroform-d(1) solution into the cyclic 1,2-dihydroquinazolin-4-one form has been studied. The structure of the obtained compounds was demonstrated by methods of H-1 and C-13 NMR spectroscopy.

  DOI：

  10.1007/s10593-009-0364-x
• 作为产物：
  描述：

  2-amino-N-(ethylideneamino)benzamide 以 氘代氯仿 为溶剂， 反应 336.0h， 以98%的产率得到2-methyl-1,2-dihydroquinazolin-4(3)-one
  参考文献：
  名称：

  Anthranoylhydrazones of aliphatic aldehydes and their cyclization to quinazolin-4-one derivatives

  摘要：

  The isomeric transition of 2-aminobenzoylhydrazones of aliphatic aldehydes 2-H2NC6H4CONHN=CHAlk (Alk = Me, Et, Pr, Bu) in chloroform-d(1) solution into the cyclic 1,2-dihydroquinazolin-4-one form has been studied. The structure of the obtained compounds was demonstrated by methods of H-1 and C-13 NMR spectroscopy.

  DOI：

  10.1007/s10593-009-0364-x

文献信息

• POLYESTER HAVING A REDUCED LEVEL OF ACETALDEHYDE
  申请人：Colormatrix Holdings, Inc.

  公开号：EP3789449A2

  公开（公告）日：2021-03-10

  A polyester, having a reduced level of acetaldehyde, said polyester incorporating a compound (A) or a product of a reaction between compound (A) and aldehyde, wherein compound (A) includes: first, second and third fragments which comprise a moiety and a moiety          NH     (B).

  一种聚酯，其乙醛含量降低，所述聚酯中含有化合物（A）或化合物（A）与醛反应的产物，其中化合物（A）包括：第一、第二和第三片段，这些片段由一个分子组成 和一个分子 NH (B)。
• METHOD OF DECREASING ALDEHYDE CONTENT IN A POLYMERIC MATERIAL
  申请人：Colormatrix Holdings, Inc.

  公开号：EP3337849B1

  公开（公告）日：2020-11-04
• [EN] METHOD OF DECREASING ALDEHYDE CONTENT IN A POLYMERIC MATERIAL<br/>[FR] PROCÉDÉ PERMETTANT D'ABAISSER LA TENEUR EN ALDÉHYDES DANS UN MATÉRIAU POLYMÈRE
  申请人：COLORMATRIX HOLDINGS INC

  公开号：WO2017033117A1

  公开（公告）日：2017-03-02

  A method of decreasing aldehyde content in polymeric materials, for example in bottles comprising polyethylene terephthalate, uses a compound (A) which comprises first, second and third fragments which comprise a moiety Fomula A) (A) and a moiety. (Formula B) NH (B).